Synthesis of Every Kinds of Peptide Fragments of Bradykinin
スポンサーリンク
概要
- 論文の詳細を見る
Synthesis of every kinds of peptide fragments of bradykinin and results of the biological activities of the synthetic bradykinin fragments on contracting effect of a guinea pig ileum, inframmatory activity on rat's hind paw and vasodilation on rat are described. So far as concerning with the contracting effect, the active site of bradykinin seems to be the phenylalanylserylprolylphenylalanine moiety. The inflammatory activity is fairy high as compared with that of bradykinin.
- 公益社団法人日本薬学会の論文
- 1969-08-25
著者
-
鈴木 謙次
Tohoku College of Pharmacy
-
遠藤 信義
Tohoku College of Pharmacy
-
安孫子 敬
Kidney Research Laboratory Kojinkai
-
安孫子 敬
Tohoku College of Pharmacy
関連論文
- Synthesis of Carboxyl-Terminal Extension Analogs of Dermorphin and Evaluation of Their Opioid Receptor-Binding and Opioid Activities
- Degradation of Deltorphins and Their Analogs by Rat Brain Synaptosomal Peptidases
- Solid-Phase Synthesis and Opioid Activities of [D-Ala^2]Deltorphin II Analogs
- Studies on Analgesic Oligopeptides. VII. Solid Phase Synthesis and Biological Properties of Tyr-D-Arg-Phe-βAla-NH_2 and Its Fluorinated Aromatic Amino Acid Derivatives
- Solid Phase Synthesis and Opioid Receptor Binding Properties of Presumable Dermorphin Precursor Derivatives
- Solid Phase Synthesis and Opioid Receptor Binding Activities of[D-Ala^2,D-Leu^5]Enkephalin Analogs Containing a Fluorinated Aromatic Amino Acid
- Studies on Analgesic Oligopeptides. VI. : Further Studies of Synthesis and Biological Properties of Tripeptide Alkylamides, Try-D-Arg-Phe-X
- Studies on analgesic Oligopeptides. V. : Structure-Activity Relationship of Tripeptide Alkylamides, Tyr-D-Arg-Phe-X
- Studies on Analgesic Oligopeptides. IV. Synthesis and Analgesic Activity of N-Terminal Shorter Analogs of [D-Arg^2] Dermorphin and Des-Tyr^1-Dermorphin Analogs
- Studies on Analgesic Oligopeptides. III. Synthesis and Analgesic Activity after Subcutaneous Administration of [D-Arg^2] dermorphin and Its N-Terminal Tetrapeptide Analogs
- Studies on Analgesic Oligopeptides. II. Structure-Activity Relationship among Thirty Analogs of a Cyclic Dipeptide, Cyclo (-Tyr-Arg-)
- Structure and Analgesic Activity Relationship of Cyclo-Tyrosyl-Arginyl and Its Three Stereoisomers
- Acetic Acid-Catalyzed Diketopiperazine Synthesis
- The β-p-Nitrobenzyl Ester to Minimize Side Reaction during Treatment of Aspartyl Peptides with Methanesulfonic Acid
- Selective Cleavage of tert-Butyloxycarbonyl Protecting Group with Dilute Organic Sulfonic Acid without Decomposition of Tryptophan Residue
- The γ-Phenacyl and γ-p-Nitrobenzyl Esters to Minimize Side Reactions during Treatment of Glutamyl Peptides with Hydrogen Fluoride-Anisole Mixture
- Study on Influence of Synthetic Glucagon Fragment on Lymphocyte Transformation. I
- Synthesis of Rat Parathymosin α Fragment 1-28 and Examination of Its Inhibitory Activity towards the Restoring Activity of Thymosin α_1 on the Impaired T-Lymphocytes of Uremic Patients
- Synthesis of an Immunologically Active Fragment Analog of Prothymosin α with Enhanced Enzymatic Stability
- Immunological Effect of Two Synthetic Peptides Containing Alanine or D-Alanine Instead of Acetyl Group of Thymosin β_4 after Treatment of Human Serum
- Synthesis of a Thymosin β_4-Like Peptide, Thymosin β^_9,and Its Effect on Low E-Rosette-Forming Lymphocytes of Lupus Nephritis Patients
- Synthesis of Human Splenin (hSP) and Examination of Its Immunological Effects on the Impaired T-and B-Lymphocytes in Uremic Patients
- Syntheses and Effects of Human Splenin (hSP) Fragment 32-48 and an Analog on the Reduced B-Lymphocytes of Uremic Patients
- Synthesis of a Thymosin β_4-Like Peptide, Deacetyl-thymosin β^_4,and Its Restorative Effect on Depressed Lymphocyte Blastogenic Response to Phytohemagglutinin (PHA) in Uremic Patients
- Synthesis of [Glu^]Human Splenin (hSP) and Examination of Its Immunological Effect on the Reduced B-Lymphocytes of Uremic Patients
- Synthesis of Human Thymopoietin (hTP) and Examination of Its Immunological Effect on the Impaired Blastogenic Response of T-Lymphocytes of Uremic Patients
- Synthesis of Deacetyl-thymosin β_7 and Examination of Its Immunological Effect on the Blastogenic Response of T-Lymphocytes of a Uremic Patient with Cell-Mediated Immunodeficiency
- Synthesis of the Revised Amino Acid Sequence of Thymopoietin II and Examination of Its Immunological Effect on the Impaired T-Lymphocyte Transformation of a Uremic Patient with Pneumonia(Biological)
- Synthesis of Deacetyl-thymosin β_ and Examination of Its Immunological Effect on T-Cell Subpopulations of a Uremic Patient with Tuberculosis
- Synthesis of the Nonatetracontapeptide Corresponding to the Entire Amino Acid Sequence of Thymopoietin III and Its Effect on the Impaired T-Lymphocyte Transformation of a Patient with Common Variable Immunodeficiency
- Synthesis and Immunological Effect of Deacetyl-thymosin α_ on Low E-Rosette-Forming Cells of a Rheumatoid Arthritis Patient
- Synthesis of the Nonatetracontapeptide Corresponding to the Entire Amino Acid Sequence of Thymopoietin I and Its Effect on the Low E-Rosette-Forming Cells of a Uremic Patient
- Deacetyl-thymosin β_4 : Synthesis and Effect on the Impaired Peripheral T-Cell Subsets in Patients with Chronic Renal Failure
- Synthesis of Six Common Amino Acid Sequence Fragments of Thymosins β_4,β_8 and β_9 and Determination of Their Effects on the Low E-Rosette Forming Cells of Lupus Nephritis Patients
- Synthesis of the Nonatriacontapeptide corresponding to the Entire Amino Acid Sequence of Calf Thymosin β_8 and Its Effect on the Impaired T-Cell Subsets in Patients with Lupus Nephritis
- Effects of Two Synthetic Serum Thymic Factor Analogues and Four Thymic Factor Fragments on the Low E-Rosette Forming Cells in Patients with Chronic Renal Failure
- Synthesis of the Octadecapeptide corresponding to Positions 32 to 49 of the Revised Amino Acid Sequence of Thymopoietin II and Its Effect on Low E-Rosette Forming Cells of an Aged Patient with Chronic Renal Failure
- The Effect of Thymosin α_1 Fragments on T-Lymphocyte Transformation in the Uremic State
- Effect of Synthetic Serum Thymic Factor Fragments on the Inhibition of Sheep Erythrocyte Rosette Formation by Uremic Toxin
- The Effect of STF and Its Analogs on T Cells with Cellular Immunodeficiency
- An Improved Attachment of N-Protected Amino Acid and Peptide to Chloromethylated Polystyrene-divinylbenzene Resin
- Tactics for Simplification of Purification Process in the Solid Phase Peptide Synthesis
- Suppression of Diketopiperazine Formation in Solid Phase Peptide Synthesis
- Synthesis of Tryptic Peptides of Hen Egg Lysozyme (Positions 1-5 and 69-73) and Related Peptides
- Studies on Encephalitogenic Fragments of Myelin Protein. I. Synthesis of Tryptophan-containing Fragments
- Synthesis of Every Kinds of Peptide Fragments of Bradykinin
- The β-Phenacyl and β-p-Nitrobenzyl Esters to Suppress Side Reactions during Treatment of Aspartyl Peptides with Hydrogen Fluoride
- A Study on Endocrine Disorder in Patients with Chronic Renal Failure. I. Synthesis and Biological Activity of Human Gastrin I
- Deacetyl-Thymosin α_1 : Synthesis and Immunological Effect on Lipoid Nephrosis Lymphocytes
- Effects of Synthetic Thymopoietin Fragments on Low E-Rosette Forming Cells in a Patient with Lupus Nephritis
- The Effect of Ubiquitin Hexadecapeptide Fragment on E-Rosette Forming Cells of a Uremic Patient
- Effects of Synthetic Thymopoietin II Fragments on E-Rosette Forming Cells of a Rheumatoid Arthritis Patient
- Synthesis of the Eicosapeptide corresponding to the N-Terminal Amino Acid Sequence of the Major Component of Human Lymphoblastoid Interferon
- Synthesis and Immunological Effects of Thymosin α_1 and Its Fragments on Inhibitory Factor in Minimal Change Nephrotic Syndrome
- The Effect of Thymopoietin II Fragments and Their Analogs on E-Rosette Forming Cells in the Uremic State
- Characterization of an Acidic Tripeptide in Neurotoxic Dialysate
- The Effect of a Synthetic Thymosin α_1 Fragment on the Inhibition of E-rosette Formation by the Serum of a Patient with Nephrotic Syndrome
- The Effects of Synthetic Glucagon Fragments on Glucose-6-phosphate Dehydrogenase. II
- Synthesis and Effects of Two Peptide Fragments of Thymopoietin II on E-Rosette Forming Cells in the Uremic State
- Synthesis of Bradykinyl-peptide and Peptidyl-bradykinin
- Synthesis of 4-L-Valine-6-L-Threonine-, 4-L-Isoleucine-6-L-Threonine-, 4-L-Leucine-6-L-Threonine-, 4-L-Valine-, and 4-L-Isoleucinebradykinin and Their O-Acetyl Compounds.
- Synthesis of 3-Sarcosine-, 3-Glycine-, and 3-L-Alanine-6-Glycine-Bradykinin and 3-Glycine-Bradykinin.
- Synthesis of 3-L-Lysine-bradykinin and Its O-Acetyl Compound
- Synthesis of β-Alanine-containing Analogs of Bradykinin
- Synthesis of Peptides Related to the C-Therminus of B-Peptide of Ox Co-fibrin : Positions 16〜21,15〜21,and 13〜21
- Synthesis of 4-L-Leucine-6-O-acetyl-L-serine, 4-L-Leucine, 6-O-Acetyl-L-serine Bradykinin, and Bradykinin
- Synthesis of 6-L-Lecucine, 6-O-Acetyl-L-threonine, and 6-L-Threonine-bradykinin
- Studies on Encephalitogenic Fragments of Myelin Protein. IV. Synthesis of Glycine Analogs of Tryptophan-containing Fragment
- Studies on Encephalitogenic Fragments of Myelin Protein. II. Solid Phase Synthesis of Tryptophan-containing Decapeptide
- Syntheses of [Phe (4NO_2)^5,Tyr (Me)^8]-and [Tyr (Me)^5,Phe (4NO_2)^8]-Bradykinin