Studies on Encephalitogenic Fragments of Myelin Protein. I. Synthesis of Tryptophan-containing Fragments

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概要

• 論文の詳細を見る

• Four peptides, H-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH, H-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH, H-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH and H-Arg-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH were synthesized by the classical method and tested for the induction of experimental allergic encephalomyelitis in guinea pigs. Consequently, it was found that the length limit of the peptide chain for the induction of the disease was the nonapeptide, H-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH.

• 公益社団法人日本薬学会の論文
• 1973-12-25

著者

• 鈴木 謙次

  東北薬科大学

• 佐々木 有亮

  Tohoku College of Pharmacy

• 遠藤 信義

  Tohoku College of Pharmacy

• 安孫子 敬

  Kidney Research Laboratory Kojinkai

• 有末 二郎

  Tohoku College Of Pharmacy:(pressent Address)research Laboratory Of Pollution

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