Studies on Encephalitogenic Fragments of Myelin Protein. IV. Synthesis of Glycine Analogs of Tryptophan-containing Fragment
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概要
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Synthesis of five glycine analogs of H-Arg-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH, in which amino acid residues at positions 3,6 and 7 are replaced by glycine, is reported. Correlation of structure and activity of the encephalitogenic decapeptide fragment is discussed on the basis of the activity in guinea pigs and circular dichroism spectra of the synthetic glycine analogs.
- 公益社団法人日本薬学会の論文
- 1974-09-25
著者
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