The Effect of Thymosin α_1 Fragments on T-Lymphocyte Transformation in the Uremic State
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概要
- 論文の詳細を見る
The thymosin α_1 C-terminal fragment H-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH (positions 14-28) was synthesized by a conventional method. Two thymosin α_1 fragments, H-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH (positions 19-28) and the pentadecapeptide fragment synthesized in this study, were tested for effect on lymphocyte transformation in the uremic state. The synthetic pentadecapeptide increased ^3H-thymidine incorporation into DNA in the uremic state, but the synthetic decapeptide had no effect on the ^3H-thymidine incorporation.
- 公益社団法人日本薬学会の論文
- 1980-11-25
著者
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関野 宏
Kidney Research Laboratory Kojinkai
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安孫子 敬
Kidney Research Laboratory Kojinkai
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樋口 博基
Kidney Research Laboratory Kojinkai
関連論文
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