深部培養による酢酸醗酵の動力学的研究 : (第2報)プロセス動力学

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Employing a strain Acetobacter rancens, the kinetics of acetic acid fermentation in a submerged culture were investigated. With regard to the relation between the specific growth rate (μ) and the cell concentration (X) under the influence of product inhibition, the following expression was considered to fit in approximately with the results of singlestage continuous culture experiments : [numerical formula]where P_0 is acetic acid concentration in the inflowing medium, and k_1´, k_2´, k_3´´´ and k_4´´´ are the system constants (>0). Thus, the Plot of μ vs. X deviated remarkably from the typical Herbert's μ-X plot due to product inhibition. The effect of acetic acid concentration (P) upon μ obeyed the following equation : [numerical formula] where k_3´´ and k_4´´ are the system constants (>0). The specific rate of product formation (ρ) as well as μ was greatly dependent upon the yeast extract concentration (S_Y) added to the medium. The relation of μ to S_Y was shown to be in accord with the Monod-type equation. The plot of μ vs. ρ exhibited a sort of parabolic curve whether or not the product inhibition was remarkable, i.e.[numerical formula] where b´and c are the system constants (>0). Such a type of "parabolic growth-association", in which a peak of ρ appeared in the plot, was thought to be rather common to this type of fermentation.
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