深部培養による酢酸醗酵の動力学的研究 : (第4報) 生産物阻害と酢酸への一過性適応

概要

論文の詳細を見る
The mode of product inhibition in submerged acetic acid fermentation by Acetobacter rancens was investigated. The results obtained were as follows : (1) A relatively long logarithmic growth phase was observed, even in cultures initially added with 1.3〜33 (g/l) of acetic acid. A sudden increse in μ-value was perceived in cultures with more than 17.6g/l of acetic acid added initially, and it sometimes divides the logarithmic phase into two phases : the first and the second logarithmic phase. Such a rapid increase was regarded as a result of the adaptation of cells to acetic acid after being exposed for a long time, while growing at a stuedy μ, which we call the first phase μ.(2) The relation of the initial acetic acid concentration (P_0) to the first phase μ is expressed by a mixed inhibition equation : Eq. (4) in the text.(3) The relation of μ to the increasing acetic acid concentration (P), in cultures without added acetic acid, was in accord with Eq. (7), which involves P^2 in the denominator and which is analogous to Eq. (4).(4) The second phase μ was shown to be a function of P^4,as expressed by Eq. (18) and (19).(5) The ideal value of μ_m, obtained by extrapolating Eq. (18) and (19), was always higher than the ideal μ_m value obtained from Eq. (17). It was interesting to note that the acetic acid adaptation resulted in the rise of the μ_m-value.(6) Such an acetic acid adaptation was shown to be a transient one, on the basis of repeated transfer experiments.(7) Yeast extract had a remarkable action in increasing the initial μ-value according to Eq. (4), and was effective in weakening the inhibition of acetic acid.(8) The effective part of dissolved acetic acid was revealed to be the undissociated molecule. In a lower pH range, the action of both hydrogen ion concentration and undissociated acetic acid were shown to be effective. Growth was shown to be more sensitive to acetic acid than respiration.
社団法人日本生物工学会の論文
1972-08-25

深部培養による酢酸醗酵の動力学的研究 : (第4報) 生産物阻害と酢酸への一過性適応

スポンサーリンク

概要

著者

関連論文

スポンサーリンク