食品のガス殺菌に関する研究 : (第4報)ガス殺菌剤(エポオキシド)の殺菌作用に対する2,3の影響因子について

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The present work was undertaken to study the factors affecting the sterilizing activity of gaseous sterilants viz. ethylene oxide and propylene oxide.Both ethylene and propylene oxides have a strong sterilizing activity against microorganisms contaminating various foodstuffs. It was found that their sterilizing efficacy was constant regardless of increases in epoxide concentration above certain limits as shown in Fig. 1. In order to detect the cause of this reduction of sterilizing efficacy, effects of the food layer and types of carriers such as corn starch and milk casein upon the sterilzing activity of gaseous drugs were investigated. The results shown in Table 1,2 and fig. 2 indicated that the decrease of sterilizing efficacy with an epoxide concentration above certain limits was not due to the difference in resistance against epoxide between microorganisms, but due to the action of coexisting substances and permeability of gas. Furtermore, amino acids, carbohydrates, proteins etc. had a protective action against the sterilizing effect of ethylene oxide in both treatments A and B as shown in Table 3 and this protective effect varied with the amount and type of tested materials (ref. Table 4 and Fig. 3).From these results, it seeimed reasonable to assume that the variety of sterilizing efficacy as often observed in commercial gaseous sterilization of foodstuffs and other materials was mainly due to the protective action of coexisting substances against sterilizing effect and the effect of environmental moisture as previously reported in the site of sterilizing acton of gaseous drugs. Relationship between the sterilizing efficacy and the quality of foodstuffs was investigated by the model experiment, with an industrial enzyme prepation as a model food sample.The data shown in Table 5 and Fig. 4 indicated taht gaseous sterilants seemed to be more destructive to microorganisms than to a food component (i.e. enzymatic activity in the model experiment).
社団法人日本生物工学会の論文
1968-04-25

食品のガス殺菌に関する研究 : (第4報)ガス殺菌剤(エポオキシド)の殺菌作用に対する2,3の影響因子について

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