プロピレンオキサイドガスの殺菌効果に及ぼす共存物質の影響

概要

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This paper describes the mechanism of the protective action of coexisting substances, i. e. milk casein, agar powder, cellulose powder, polyvinyl chloride powder, teflon powder and glass beads, against the sporicidal activity of gaseous propylene oxide (PO) toward Bacillus subtilis var. niger 4380 spores. The first four substances showed remarkable protective action, while the others had no effect. The isothermal PO adsorption curve of spores was of the Henry's type, so the D value of spores was dependent on the amount of adsorbed PO. But the amount of PO adsorbed by spores decreased with increasing water content of spores.When spores were exposed to gaseous PO, the amount of PO adsorbed by spores was significantly decreased in the presence of coexisting protective substances. Although spores lost the water during the gaseous PO treatment, loss of water from spores was suppressed by the coexistence of protective substances.These results indicate that the protective effect of coexisting substances is not due to the reduction of gaseous PO concentration, but to the suppression of water loss from spores during the gaseous treatment.
社団法人日本生物工学会の論文
1980-01-25