Effects of DFA IV in Rats : Calcium Absorption and Metabolism of DFA IV by Intestinal Microorganisms
スポンサーリンク
概要
- 論文の詳細を見る
Di-D-fructose-2,6' : 6,2'-dianhydride (DFA IV) is a disaccharide consisting of two fructose residues that can be prepared from levan by levan fructotransferase from Arthrobacter nicotinovorans GS-9,and it can be expected to have novel physiological functions from its unique structure. In this study, the effects of DFA IV on calcium absorption and the metabolism of DFA IV by intestinal microorganisms were studied in rats to examine the physiological functions of DFA IV. The apparent calcium absorption in rats fed with DFA IV was significantly higher than that in the control rats, and it seems that calcium absorption had almost been completed at the end of the small intestine. DFA IV also increased the calcium absorption in in vitro experiments, using everted jejunal and ileal sacs, and this result supports the finding obtained in the in vivo experiments. These results indicate that DFA IV may have a function for increasing the calcium absorption in the small intestine of rats. However, the effect in the large intestine could not be clearly observed because of the lack of calcium that reached there. The results of analyses of organic acids in the cecal and colonic contents and of DFA IV in the fecal, cecal, and colonic contents showed that the metabolism of DFA IV by microorganisms in the large intestine progressed gradually, and that DFA IV was converted mainly to acetate, butyrate, and lactate.
- 社団法人日本農芸化学会の論文
- 1999-04-23
著者
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Yokota Atsushi
Laboratory of Microbial Physiology, Research Faculty of Agriculture, Hokkaido University
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Suzuki Tomomi
School Of Agriculture Bioscience Center Nagoya University
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HARA HIROSHI
Laboratory of Nutritional Biochemistry, Graduate School of Agriculture, Hokkaido University
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TOMITA FUSAO
Laboratory of Applied Microbiology, Graduate School of Agriculture, Hokkaido University
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SAITO KATSUICHI
Laboratory of Applied Microbiology, Graduate School of Agriculture, Hokkaido University
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横田 篤
Laboratory Of Microbial Physiology Research Faculty Of Agriculture Hokkaido University
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Yokota Atsushi
Lab. Of Microbial Physiology Res. Fac. Of Agriculture Hokkaido Univ. Kita 9 Nishi 9 Kita-ku Sapporo
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横田 篤
北大 大学院農学研究院
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Yokota Atsushi
Laboratory Of Bioorganic Chemistry
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Yokota A
Laboratory Of Applied Microbiology Department Of Bioscience And Chemistry Faculty Of Agriculture Hok
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Yokota Atsushi
Laboratory Of Applied Microbiology Department Of Bioscience And Chemistry Faculty Of Agriculture Hok
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Tomita Fusao
Laboratory Of Applied Microbiology
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Tomita Fusao
Department Of Agricultural Chemistry Faculty Of Agriculture Hokkaido University
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Sugiyama Tatsuo
Riken Plant Science Center
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Saito Katsuichi
Department Of Upland Agriculture National Agricultural Research Center For Hokkaido Region
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Saito Katsuichi
Memuro Upland Farming Research Station National Agricultural Research Center For Hokkaido Region
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Saito Katsuichi
Laboratory Of Applied Microbiology Graduate School Of Agriculture Hokkaido University
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Suzuki T
Division Of Marine Life Sciences Grauate School Of Fisheries Science Hokkaido University
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Yokota A
Hokkaido Univ. Hokkaido Jpn
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Hara Hiroshi
Toxicology Laboratory Chugai Pharmaceutical Co. Ltd.
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Saito K
Department Of Upland Agriculture National Agricultural Research Center For Hokkaido Region
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HIRA Toru
Laboratory of Nutritional Biochemistry, Department of Bioscience and Chemistry, Faculty of Agricultu
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SUZUKI Takuya
Laboratory of Nutritional Biochemistry, Department of Bioscience and Chemistry, Faculty of Agricultu
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Hira T
Hokkaido Univ. Sapporo Jpn
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Hara Hiroshi
Laboratory Of Nutritional Biochemistry Division Of Applied Bioscience Graduate School Of Agriculture
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Sugiyama Tatsuo
Dept.appl.biol.sci. Sch.agrc.sci. Nagoya Univ.
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