Peroxynitrite Scavengers Produced by Filamentous Fungus Used in the Katsuobushi Manufacturing Process
スポンサーリンク
概要
- 論文の詳細を見る
Extracts of Aspergillus spp., Monascus purpureus, Rhizopus microsporus, and Eurotium repens, which are filamentous fungi used in the manufacture of fermented foods including sake, shoyu, miso, shochu, tofuyo, tempeh and katsuobushi, were examined for peroxynitrite scavenging activity. Extracts of Eurotium repens, used in the molding step in the manufacture of katsuobushi, exhibited the highest activity of all the tested extracts. Peroxynitrite scavengers were isolated from Eurotium repens extract and were identified as auroglaucin, dihydroauroglaucin, isodihydroauroglaucin, tetrahydroauroglaucin and flavoglaucin. Tetrahydroauroglaucin exhibited the highest peroxynitrite scavenging activity of the isolated compounds, and showed suppressive effects on the expression of blood adhesion molecules, intercellular adhesion molecule-1 (ICAM-1) and vascular adhesion molecule-1 (VCAM-1), in human umbilical vein endothelial cells (HUVECs) after induction with tumor necrosis factor (TNF-α).
- 社団法人 日本食品科学工学会の論文
- 2010-09-01
著者
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MIYAKE Yoshiaki
Faculty of Human Wellness, Tokaigakuen University
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OSAWA Toshihiko
Laboratory of Food and Biodynamics, Graduate School of Bioagricultural Sciences, Nagoya University
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大沢 俊彦
名古屋大学大学院生命農学研究科
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ITO Chihiro
Faculty of Pharmacy, Meijo University
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Ito Chihiro
Faculty Of Pharmacy Meijo University
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Osawa Toshihiko
Lab. Of Food And Biodynamics Graduate School Of Bioagricultural Sciences Nagoya Univ.
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Osawa T
Laboratory Of Food And Biodynamics Nagoya University Graduate School Of Bioagricultural Sciences
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Miyake Y
Central Research Laboratory Of Pokka Corporation Ltd.
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Miyake Yoshiaki
Faculty Of Human Wellness Tokaigakuen University
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ITOIGAWA Masataka
Faculty of Human Wellness, Tokaigakuen University
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MOCHIZUKI Mika
Faculty of Human Wellness, Tokaigakuen University
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Mochizuki Mika
Faculty Of Psychological And Physical Science Aichi Gakuin University
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Osawa Toshihiko
Laboratory Of Food And Bio-dynamics Nagoya University
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Itoigawa Masataka
Faculty Of Human Wellness Tokaigakuen University
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Itoigawa Masataka
Faculty Of Human Wellness Tokai Gakuen University
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