The Metabolic Conversion of 9, 11, 13-Eleostearic Acid (18 : 3) to 9, 11-Conjugated Linoleic Acid (18 : 2) in the Rat
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概要
- 論文の詳細を見る
The presence of a significant amount of 9, 11-conjugated linoleic acid (CLA, 9, 11-18%2) was confirmed in the liver and plasma lipids of rats fed a 1% (w/w % of diet) eleo-stearic acid (ESA, 9, 11, 13-18 e 3 ) diet for 4 wk, The chemical structure of the 9, 11-CLA apparent in the tissue lipids was identified by gas chromatography-electron impact mass spectrometry after its conversion to a 4, 4-dimethyloxazoline derivative. The concentration of CLA in the total fatty acids of the liver and plasma lipids reached to about 1% for each in the CLA-supplemented rats, while reaching 3.2% and 2.5%, respectively, in the ESA-supplemented rats, The results suggest that α-ESA is metabolized partially to CLA via a delta 13-saturation reaction in the rat. Some biological activities observed in α-ESA-fed animals may be ascribed also to CLA that is formed from ESA in the body.
- 財団法人 学会誌刊行センターの論文
- 2003-06-01
著者
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Komai Michio
Laboratories Of Nutrition Graduate School Of Life Science And Agriculture Tohoku University
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Miyazawa Teruo
Biodynamic Chemistry Graduate School Of Life Sci. And Agriculture Tohoku Univ.
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Miyazawa T
Tohoku Univ. Miyagi Jpn
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Miyazawa T
Tohoku Univ. Sendai Jpn
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Miyazawa Teruo
Department Of Food Chemistry Faculty Of Agriculture Tohoku University
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Igarashi Miki
Biodynamic Chemistry, Graduate School of Life Science and Agriculture, Tohoku University
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TSUZUKI Tsuyoshi
Laboratories of Food & Biodynamic Chemistry, Graduate School of Life Science and Agriculture, Tohoku
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IGARASHI Miki
Laboratories of Food & Biodynamic Chemistry, Graduate School of Life Science and Agriculture, Tohoku
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Miyazawa Teruo
Laboratory Of Biodynamic Chemistry Graduate School Of Life Science And Agriculture Tohoku University
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Igarashi Miki
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Miyazawa Teruo
Tohoku Univ.
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Tsuzuki Tsuyoshi
Food And Biomolecular Science Graduate School Of Life Science And Agriculture Tohoku University
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Tsuduki Tsuyoshi
Laboratory Of Food And Biomolecular Science Graduate School Of Agriculture Tohoku University
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Masuko Tsuyoshi
Department Of Surgery Division Gi And Colorectal Surgery Research Unit Of Biological Regulation And
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Masuko Tsuyoshi
Department Of Surgery Tohoku University Graduate School Of Medicine
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TSUZUKI Tsuyoshi
Laboratories of 1 Food & Biodynamic Chemistry Tohoku University
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IGARASHI Miki
Laboratories of 1 Food & Biodynamic Chemistry Tohoku University
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MIYAZAWA Teruo
Laboratories of 1 Food & Biodynamic Chemistry Tohoku University
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