Effect of Dietary Oils on Host Resistance to Fungal Infection in Psychologically Stressed Mice

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概要

• 論文の詳細を見る

• Psychological stress can modulate host defense against invading pathogens. In this study, we investigated the effect of dietary oils on social isolation stress-induced modulation of host resistance to Paracoccidioides brasiliensis. In olive oil-fed mice, 3 weeks of isolation stress resulted in temporarily delayed clearance of this fungus in the liver compared with group-housed mice. By contrast, in soybean oil-fed mice, isolation stress had no significant effect on antifungal activity. The olive oil-fed mice showed greater liver interferon (IFN)-γ and interleukin (IL)-6 production in response to infection as compared with the soybean oil-fed mice. In the olive oil-fed mice, isolation stress led to greater infection-induced IFN-γ production in the liver compared with the group-housed animals. These results indicate that the modulatory effects of psychological stress on host resistance to P. brasiliensis can vary depending on dietary fatty acid composition.

• 社団法人 日本農芸化学会の論文
• 2009-09-23

著者

• Tsuzuki Tsuyoshi

  Food & Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University

• Miyazawa Teruo

  Biodynamic Chemistry Graduate School Of Life Sci. And Agriculture Tohoku Univ.

• Miyazawa T

  Tohoku Univ. Miyagi Jpn

• Miyazawa T

  Tohoku Univ. Sendai Jpn

• Miyazawa Teruo

  Department Of Food Chemistry Faculty Of Agriculture Tohoku University

• NAKAGAWA Kiyotaka

  Biodynamic Chemistry Lab, Graduate School of Agricultural Science, Tohoku University

• HIRASAKA Katsuya

  Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima G

• NIKAWA Takeshi

  Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima G

• Oarada Motoko

  Medical Mycology Research Center, Chiba University

• Igarashi Miki

  Biodynamic Chemistry, Graduate School of Life Science and Agriculture, Tohoku University

• KAMEI Katsuhiko

  Medical Mycology Research Center, Chiba University

• GONOI Tohru

  Medical Mycology Research Center, Chiba University

• KURITA Nobuyuki

  Medical Mycology Research Center, Chiba University

• Gonoi Tohru

  Medical Mycology Res. Center Chiba Univ.

• Nakagawa K

  Biodynamic Chemistry Graduate School Of Life Sci. And Agriculture Tohoku Univ.

• Igarashi Miki

  Division Of Biochemistry Faculty Of Fisheries Nagasaki University

• Nikawa T

  Dep. Of Nutrition Tokushima Univ. School Of Medicine

• Nikawa Takeshi

  Department Of Nutrition School Of Medicine The University Of Tokushima

• Kishi Kyoichi

  Department Of Nutritional Physiology Institute Of Health Biosciences The University Of Tokushima Gra

• Miyazawa Teruo

  Tohoku Univ.

• Kamei Katsuhiko

  Medical Mycology Research Center Chiba University

• Igarashi Miki

  Biodynamic Chemistry Graduate School Of Life Science And Agriculture Tohoku University

• Oarada Motoko

  Medical Mycology Research Center Chiba University

• Gonoi Tohru

  Medical Mycology Research Center Chiba University

• Tsuzuki Tsuyoshi

  Food And Biomolecular Science Graduate School Of Life Science And Agriculture Tohoku University

• Kurita Nobuyuki

  Medical Mycology Research Center Chiba University

• Hirasaka Katsuya

  Department Of Nutrition Tokushima University School Of Medicine

• Hirasaka Katsuya

  Department Of Nutrition The University Of Tokushima Faculty Of Medicine

• Tsuduki Tsuyoshi

  Laboratory Of Food And Biomolecular Science Graduate School Of Agriculture Tohoku University

• Masuko Tsuyoshi

  Department Of Surgery Division Gi And Colorectal Surgery Research Unit Of Biological Regulation And

• Masuko Tsuyoshi

  Department Of Surgery Tohoku University Graduate School Of Medicine

• Kamei Katsuhiko

  Medical Mycology Res. Center Chiba Univ.

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