Lung Nocardia elegans Infection Diagnosed on Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS)
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概要
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A 73-year-old man with adultonset Still's disease developed a high fever, coughing, dyspnea and bloody sputum and was therefore admitted to our hospital. Thoracic X-ray and CT scans revealed oval lesions in the bilateral lungs. A bacterial isolate from the sputum was identified to be Nocardia elegans (N. elegans) on comparative 16S rRNA gene sequencing and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS). The patient recovered following treatment with imipenem/cilastatin and amikacin. To the best of our knowledge, this is the first case of nocardiosis caused by N. elegans identified on MALDI-TOF MS.
- 一般社団法人 日本内科学会の論文
著者
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Gonoi Tohru
Medical Mycology Res. Center Chiba Univ.
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Nakanishi Toyofumi
Department Of Clinical And Laboratory Medicine Osaka Medical College
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Higashiyama Tomohiro
Department of Clinical and Labolatory Medicine, Osaka Medical College, Japan
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Ukimura Akira
Infection Control Office, Osaka Medical College Hospital, Japan
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Nagai Koji
Division of Rheumatology, Osaka Medical College Hospital, Japan
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Ooi Yukimasa
Infection Control Office, Osaka Medical College Hospital, Japan
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Shiba Hideyuki
Division of Rheumatology, Osaka Medical College Hospital, Japan
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Nakano Takashi
Infection Control Office, Osaka Medical College Hospital, Japan
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- Lung Nocardia elegans Infection Diagnosed on Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS)