Lupeol Supplementation Improves Blood Pressure and Lipid Metabolism Parameters in Stroke-Prone Spontaneously Hypertensive Rats

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概要

• 論文の詳細を見る

• Supplementation with lupeol (0.67 g·kg<SUP>－1</SUP>) of the AIN-93M-based diet fed for 7 weeks to stroke-prone spontaneously hypertensive rats caused significantly decreased blood pressure as compared with a control group. Urinary 8-hydroxy-2′-deoxyguanosine was significantly lower in the lupeol group. Finally, lupeol suppressed the hepatic mRNA expression levels of the genes involved in triglyceride and cholesterol synthesis.

著者

• KOMAI Michio

  Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University

• Hata Keishi

  Akita Res. Inst. For Food And Brewing (arif)

• Hiwatashi Kazuyuki

  Akita Res. Inst. Of Food And Brewing

• Komai Michio

  Laboratories Of Nutrition Graduate School Of Life Science And Agriculture Tohoku University

• Goto Tomoko

  Laboratory Of Nutrition

• Shirakawa Hitoshi

  Laboratory Of Nutrition

• Ohinata Kousaku

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

• Yamaguchi Eri

  Laboratory Of Nutrition Graduate School Of Agricultural Science Tohoku University

• HIWATASHI Kazuyuki

  Akita Research Institute for Food and Brewing

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