Possible Involvement of Plasmid in Nucleotide Pyrophosphokinase Production and the Relationship between this Productivity and Cellular Accumulation of Guanosine Tetraphosphate (ppGpp) in Streptomycetes
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概要
- 論文の詳細を見る
The possible physiological function of nucleotide pyrophosphokinase (EC 2.7.6.4) which synthesizes a great variety of 3-pyrophosphorylated nucleotides, including ppGpp, pppGpp and pppApp has been studied. Acriflavin treatment eliminated the production of this enzyme by Streptomyces morookaensis and suggests the possible involvement of plasmid: Irrespective of the ability to produce the enzyme, all Streptomyces species so far tested accumulated ppGpp and some pppGpp, whereas other highly phosphorylated nucleotides could not be detected. Furthermore, both the enzymeproducing and non-producing strains accumulated similar quantities of ppGpp. These results indicate that the enzyme does not operate in vivo, at least under normal growth conditions.
- 社団法人 日本農芸化学会の論文
著者
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Murao Sawao
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Nishino Toyokazu
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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