Uptake and Re-secretion of Human Lactoferrin by B Lymphocytes(Biological Chemistry)
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概要
- 論文の詳細を見る
An electron microscopic observation using anti-human lactoferrin (LF) and gold probe and a reverse hemolytic plaque assay using anti-LF serum were done with the aim of clarifying uptake of LF by B lymphocytes and its release from the cells. The electron microscopic observation clearly demonstrated the occurrence of LF inside of the B lymphocyte. The number of LF-secreting cells, measured by a reverse hemolytic plaque assay, varied with cell types; a human-human hybridoma 9P-13-2 showed the highest number, but the number was much lower with a mouse myeloma. The number of LF-secreting cells increased in proportion to the incubation period with LF. From these results, we concluded that B lymphocytes incorporated LF and then re-secreted it gradually to the extracellular minium.
- 社団法人日本農芸化学会の論文
- 1990-05-23
著者
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Sato Kenji
Department Of Food Sciences And Nutritional Health Kyoto Prefectural University
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SHINMOTO Hiroshi
Technical Research Institute, Snow Brand Milk Products Co., Ltd.
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Hirose S
Tokachi‐ikeda Research Inst. Viticulture And Enology Hokkaido Jpn
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NAKAJIMA ICHIRO
Technical Research Institute, Snow Brand Milk Products Co. Ltd.,
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Sato K
Department Of Food Sciences And Nutritional Health Kyoto Prefectural University
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Kubota S
Division Of Human Health And Medical Science Graduate School Of Kuroshio Science Kochi University
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Shinmoto H
Snow Brand Milk Products Co. Ltd. Kawagoe Jpn
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Tanimoto Morimasa
Technical Research Institute, Snow Brand Milk Products Co., Ltd.
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SATO Kaoru
Technical Research Institute, Snow Brand Milk Products Co., Ltd.
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Nakajima I
Snow Brand Milk Products Co. Ltd. Saitama Jpn
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Tanimoto Morimasa
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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Sato Kaoru
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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Dosako S
Snow Brand Co. Ltd. Saitama Jpn
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Nakajima Ichiro
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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Shinmoto Hiroshi
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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