Inhibition by Lactoferrin and κ-Casein Glycomacropeptide of Binding of Cholera Toxin to its Receptor
スポンサーリンク
概要
- 論文の詳細を見る
Inhibition from binding of Cholera toxin (CT) to Chinese hamster ovary (CHO) -k1 cells and ganglioside G_<M1> by lactoferrin (Lf) and κ-casein glycomacropeptide (GMP) from cow's milk was examined. Both Lf and GMP effectively reduced the CT-derived morphological changes in CHO-K1 cells. The competitive binding assay demonstrated that both Lf and GMP inhibited the binding of CT to G_<M1>, although their affinity for CT was lower than that of G_<M1>. The inhibitory effect of Lf and GMP seemed to be attributed to their terminal sialic acid, although the sugar chain sequence only partially fitted to the CT-receptor.
- 社団法人日本農芸化学会の論文
- 1992-02-23
著者
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KAWASAKI Yoshihiro
Technology and Research Institute, Snow Brand Milk Products Co., Ltd.
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Isoda H
Univ. Tsukuba Ibaraki Jpn
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Isoda H
Snow Brand Milk Products Co. Kawagoe Jpn
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Isoda Hiroko
Technical Research Institute Snow Brand Milk Products Co.
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Idota T
Snow Brand Milk Products Co. Ltd. Saitama Jpn
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Idota Tadashi
Technical Research Lnstitute Snow Brand Milk Products Co. Ltd.
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Idota Tadashi
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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KAWASAKI Yoshihiro
Fujitsu Laboratories Ltd., Wireless Communication Systems Laboratories
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Kawasaki Yoshihiro
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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Kawasaki Yoshihiro
Fujitsu Laboratories Ltd. Wireless Communication Systems Laboratories
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Kawasaki Yoshihiro
Technical Research Institute Snow Brand Milk Products Co.
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Kawasaki Y
Snow Brand Milk Products Co. Ltd. Saitama Jpn
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Isoda Hiroko
Sapporo Research Laboratory, Snow Brand Milk Products Co., Ltd.
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Tanimoto Morimasa
Technical Research Institute, Snow Brand Milk Products Co., Ltd.
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AHIKO Kenkichi
Sapporo Research Laboratory, Snow Brand Milk Products Co., Ltd.
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Ahiko Kenkichi
Sapporo Research Laboratory Snow Brand Milk Products Co. Ltd.
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Tanimoto Morimasa
Technical Research Institute Snow Brand Milk Products Co. Ltd.
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Dosako S
Snow Brand Co. Ltd. Saitama Jpn
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