Anti-androgenic and Hair Growth Promoting Activities of Lygodii Spora (Spore of Lygodium japonicum)I. : Active Constituents Inhibiting Testosterone 5α-Reductase

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概要

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• The aqueous ethanol extract of Lygodii Spora (spore of Lygodium japonicum (Thunb.) Sw.) showed in vitro testosterone 5α-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice. From the lipophilic constituents of Lygodii Spora, oleic, linoleic and palmitic acids were identified as the main active principles inhibiting testosterone 5α-reductase.

• 公益社団法人日本薬学会の論文
• 2002-05-01

著者

• 山崎 幹夫

  千葉大学薬学部

• 角谷 真

  京都薬科大学

• Naruto Shunsuke

  Faculty of Pharmacy, Kinki University

• Matsuda Hideaki

  Faculty of Pharmacy, Kinki University

• Naruto S

  School Of Pharmacy Kinki University

• Naruto Shunsuke

  近畿大学 薬学部薬用資源学研究室

• Kubo M

  School Of Pharmaceutical Sciences Kinki University

• Kubo Michinori

  近畿大学 薬学部

• KUBO Michinori

  Faculty of Pharmaceutical Sciences, Kinki University

• Kubo Michinori

  Kyoto Pharmaceutical University

• Kubo Michinori

  Faculty Of Pharmaceutical Sciences Kinki University

• YAMAZAKI Miho

  School of Pharmaceutical Sciences, Kinki University

• Yamazaki M

  School Of Pharmaceutical Sciences Kinki University

• Yamazaki Miho

  Faculty Of Agriculture And Life Science Hirosaki University

• Matsuda Hideaki

  Faculty Of Pharmaceutical Sciences Kinki University

• ASANUMA Yusuke

  Daiichi Pharmaceutical Co., Ltd.

• Kubo M

  Kampo And Pharmacognosy Laboratory Tsumura And Co.

• Kubo M

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Asanuma Yusuke

  Daiichi Pharmaceutical Co. Ltd.

• Naruto Shunsuke

  Faculty Of Pharmacy Kinki University

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