A New Series of Coumarin Derivatives Having Monoamine Oxidase Inhibitory Activity from Monascus anka
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概要
- 論文の詳細を見る
Monankarins A-F (1-6), a new series of pigments having conjugated pyrano-coumarin skeleton have been isolated from Monascus anka. Their structures have been elucidated by spectroscopic means and chemical modification. Monankarins A-D exhibited monoamine oxidase (MAO) inhibitory activity, while the activity was not observed in monankarins E and F or some other simple coumarins. Monankarin C (3) showed stronger inhibition of MAO-B than MAO-A in mice brain. However, the specificity was not found in mice liver MAO.
- 公益社団法人日本薬学会の論文
- 1996-08-15
著者
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山崎 幹夫
千葉大学薬学部
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山崎 幹夫
千葉大学薬学部医薬品素材学講座
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奥山 恵美
千葉大学 院薬
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HOSSAIN Chowdhury
Faculty of Pharmaceutical Sciences, Chiba University
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OKUYAMA Emi
Faculty of Pharmaceutical Sciences, Chiba University
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YAMAZAKI Mikio
Faculty of Pharmaceutical Sciences, Chiba University
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Okuyama Emi
Faculty Of Pharmaceutical Science Chiba University
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OKUYAMA Emi
Laboratory of Pharmacognosy, Faculty of Pharmaceutical Sciences, Josai International University
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Okuyama E
Laboratory Of Pharmacognosy Faculty Of Pharmaceutical Sciences Josai International University
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Yamazaki Mikio
Faculty Of Pharmaceutical Sciences Chiba University
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Hossain Chowdhury
Faculty Of Pharmaceutical Sciences Chiba University
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