A New Sensitive Derivatization Reagent for Liquid Chromatographic Separation of Hydroxyl Compounds
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概要
- 論文の詳細を見る
A new sensitive derivatization reagent for use in liquid chromatographic separation of hydroxyl compounds has been developed. A suitable reagent for this purpose, 4-dimethylamino-1-naphthoyl nitrile, was readily prepared from the corresponding acid chloride by the exchange reaction with trimethylsilyl cyanide. Condensation of a hydroxyl compound with the reagent was effected in the presence of triethylamine under the mild condition. The resulting ester was highly responsible for a fluorescence detector with a detection limit of 200 pg.
- 公益社団法人日本薬学会の論文
- 1981-03-25
著者
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南原 利夫
Pharmaceutical Institute, Tohoku University
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後藤 信治
Pharmaceutical Institute Tohoku University
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後藤 順一
Pharmaceutical Institute Tohoku University
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南原 利夫
東北大学医学部薬学科
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南原 利夫
Pharmaceutical Institute Tohoku University
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小松 栄
Pharmaceutical Institute, Tohoku University
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小松 栄
Pharmaceutical Institute Tohoku University
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