Blockage of Coordination with Shift Reagent by tert-Butyldimethylsilylation in Nuclear Magnetic Resonance Spectroscopy and Its Applications to Deuterium-Labeled Steroids
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概要
- 論文の詳細を見る
Derivatization of a hydroxyl group into the tert-butyldimethylsilyl ether was shown to be useful for selective blockage of coordination of the substrate with the lanthanide shift reagent in ^1H nuclear magnetic resonance spectroscopy. This method was conveniently applied to confirmation of the labeled position with deuterium in the dioxygenated steroids.
- 公益社団法人日本薬学会の論文
- 1977-10-25
著者
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南原 利夫
Pharmaceutical Institute, Tohoku University
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山下 幸和
Pharmaceutical Institute Tohoku University
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山下 幸和
日本化薬(株)医薬事業本部総合研究所
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南原 利夫
Pharmaceutical Institute Tohoku University
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