Selective Substitution Reactions of Quinoline Derivatives by Redox Systems Nucleophilic Character of Hydroxyalkyl Radicals
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概要
- 論文の詳細を見る
Homolytic hydroxyalkylation of quinoline derivatives by redox systems is described. The direct introduction of hydroxyalkyl groups into heteroaromatic ring of quinoline derivatives has been achieved by means of hydrogen peroxide. The good yields and the complete selectivity obtained are due to the nucleophilic character at heteroaromatic ring of the hydroxyalkyl radicals. It is useful to apply this reaction to other synthetic reactions.
- 公益社団法人日本薬学会の論文
- 1975-03-25
著者
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三橋 進
東京薬科大学:(現)東菱薬品工業(株)大森研究所
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川添 豊
Faculty of Pharmaceutical Sciences, Nagoya City University
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川添 豊
National Cancer Center Research Institute
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糸川 秀治
Tokyo College Of Pharmacy
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川添 豊
Faculty Of Pharmaceutical Sciences Nagoya City University
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糸川 秀治
東京薬科大学 薬学部
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三橋 進
Tokyo College of Pharmacy
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田崎 敏夫
東京薬科大学
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