Biotransformation of Cannabinoid Precursors and Related Alcohols by Suspension Cultures of Callus induced from Cannabis sativa L.
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概要
- 論文の詳細を見る
In the suspension cultures using callus induced from Cannabis sativa L., geraniol, nerol, olivetol and ethyl olivetolate which are cannabinoid precursors were not biotransformed to cannabinoids. We found that primary and secondary allylic alcohols such as geraniol, nerol, trans-cinnamyl alcohol, isophorol and trans-verbenol were biotransformed to the corresponding aldehydes. On the other hand, acyclic secondary allylic alcohols such as α-ionol, β-ionol and 4-phenyl-3-buten-2-ol were not biotransformed. Further, we clarified that the enzyme which catalyzed the oxidation of allylic alcohols was an alcohol oxidase.
- 公益社団法人日本薬学会の論文
- 1977-08-25
著者
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三橋 進
東京薬科大学:(現)東菱薬品工業(株)大森研究所
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糸川 秀治
Tokyo College Of Pharmacy
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糸川 秀治
東京薬科大学 薬学部
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竹谷 孝一
Tokyo College of Pharmacy
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三橋 進
Tokyo College of Pharmacy
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