24 ショウガ科植物の成分研究(口頭発表の部)

概要

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From the results of various screening tests, cytotoxicity, Sarcoma 180A, antihistamine and anti-bariumchloride, Zingiberaceous plants were assumed to be containing some kinds of active components. First of all, Curcuwa xanthorrhiza,Indonesian plant, was studied chemically and 8 kinds of bisabolane type sesquiterpenes were isolated. Two sesquiterpenes of then were observed to have strong activity against Sarcoma 180A. Alpinia spp. are widely distributed in Japan and in other tropical Countries. A. japonica was found to contain many kinds of eudesnane, agarofuran, erenophilane type sesquiterpenes. A peroxide, hanalpinol(8), obtained from the sane plant was converted into furopelargone B(13). Moreover, some kitinds of peroxide sesquiterpenes were also isolated from the sane plant, so molecular orbital calculation using MNDO method was adopted to assume the biosynthetical pathway of these peroxides. YakuchinoneA and B were isolated from A. oxyphylla as pungent principles. The former was noticed to be active for the inhibition of prostaglandin biosynthesis. Further, A. internedia, A. officinarun, A. speciosa and A. katsunadai were studied chemically and many components were isolated. Finally,Chemotaxonomical consideration was applied to Alpinia species.
天然有機化合物討論会の論文
1988-09-26