Cytotoxic Sesquiterpenes from Nardostachys chinensis
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概要
- 論文の詳細を見る
Five cytostatic sesquiterpenes, desoxo-narchinol-A (1), nardosinone (2), debilon (3), nardosinonediol (4) and kanshone A (5), were isolated from the roots and rhizomes of Nardostachys chinensis (Valerianaceae). The steric structure of 1 was determined by nuclear Overhauser effects (NOEs) and the exciton chirality method. All five showed cytotoxic activity against P-388 cells and the structure-activity relationship of 1 was also discussed.
- 公益社団法人日本薬学会の論文
- 1993-06-15
著者
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森田 博史
Department of Pharmacognosy, Tokyo College of Pharmacy
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竹谷 孝一
Department of Pharmacognosy, Tokyo College of Pharmacy
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糸川 秀治
Department of Pharmacognosy, Tokyo College of Pharmacy
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森田 博史
Department Of Pharmacognosy School Of Pharmacy Tokyo University Of Pharmacy And Life Sciences
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竹谷 孝一
東京都立衛生研究所
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糸川 秀治
東京薬科大学 薬学部
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森田 博史
東京薬科大学
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益山 光一
Department of Pharmacognosy, Tokyo College of Pharmacy
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益山 光一
Department Of Pharmacognosy Tokyo College Of Pharmacy
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