Tyrosinase Inhibitors from Crude Drugs
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概要
- 論文の詳細を見る
Various crude drugs were examined for their tyrosinase inhibitory activity. Marked activity was observed in Chouji and Yakuchi extracts and the active substances in these extracts were identified as eugenol and yakuchinone A, respectively. Other vanillyl compounds such as ferulic acid, curcumin and yakuchinone B also had higher activities than eugenol or yakuchinone A and inhibited the enzyme competitively. The presence of the hydroxyl group at the 4 position of the aromatic ring of the cinnamoyl moiety and the α, β-unsaturated carbonyl conjugated with an aromatic ring in these substances may play important roles in the competitive inhibition of tyrosinase.
- 公益社団法人日本薬学会の論文
- 1994-02-15
著者
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横倉 輝男
ヤクルト中央研究所
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横倉 輝男
Yakult Central Institute for Microbiological Research
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相山 律男
ヤクルト中央研究所
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相山 律男
Yakult Central Institute For Microbiological Research
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横倉 輝雄
Yakult Institute for Microbiological Research
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代田 幸子
Yakult Central Institute for Microbiological Research
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宮崎 幸司
Yakult Central Institute for Microbiological Research
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市岡 稔
Yakult Central Institute for Microbiological Research
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宮崎 幸司
(株)ヤクルト本社中央研究所
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横倉 輝男
ヤクルト本社 中研
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市岡 稔
(株)ヤクルト本社中央研究所
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横倉 輝男
Yakult Central Institute
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