Studies on Non-sesquiterpenoid Constituents of Gaillardia pulchella. II. Less Lipophilic Substances, Methyl Caffeate as an Antitumor Catecholic

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概要

• 論文の詳細を見る

• A less lipophilic non-sesquiterpenoid antitumor constituent, methyl caffeate, along with D-fructose, was isolated from the aqueous methanol extract of the dried whole plant of Gaillardia pulchella. Among forty-three synthetic catechol analogues related to methyl caffeate tested for antitumor activity against Sarcoma 180 in mice, acetates of methyl catecholylpropionoid type showed stronger activity than the corresponding catechuic acid and catechualdehyde derivatives as well as simple benzaldehyde (so-called vidrol). None of the catecholic and related compounds tested showed significant antimicrobial activity in vitro.

• 公益社団法人日本薬学会の論文
• 1984-03-25

著者

• 大倉 多美子

  Pharmaceutical Institute School Of Medicine Keio University

• 堀 均

  Pharmaceutical Institute School Of Medicine Keio University

• 横倉 輝男

  Yakult Central Institute for Microbiological Research

• 稲山 誠一

  Pharmaceutical Institute, School of Medicine, Keio University

• 播磨谷 健蔵

  Pharmaceutical Institute, Tohoku University

• 引地 学

  Pharmaceutical Institute, School of Medicine, Keio University

• 川又 健

  Pharmaceutical Institute, School of Medicine, Keio University

• 引地 学

  Yakult Central Institute

• 稲山 誠一

  Institute Of Oriental Medical Sciences

• 稲山 誠一

  Pharmaceutical Institute School Of Medicine Keio University

• 稲山 誠一

  慶應義塾大学医学部薬化学研究所

• 播磨谷 健蔵

  Pharmaceutical Institute School Of Medicine Keio University

• 川又 健

  Pharmaceutical Institute School Of Medicine Keio University

• 引地 学

  Pharmaceutical Institute School Of Medicine Keio University

• 横倉 輝男

  Yakult Central Institute

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