Quantitative Analysis of Tertiary and Quaternary Alkaloids in Corydalis Tuber by Ion-Pair High-Performance Liquid Chromatography and Its Application to an Oriental Pharmaceutical Preparation
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概要
- 論文の詳細を見る
A new, simple and precise method using ion-pair high-performance liquid chromatography was developed for the determination of alkaloids in Corydalis Tuber and Anchusan-to dry extract, i.e., tetrahydrocolumbamine, glaucine, tetrahydropalmatine, corydaline, columbamine, coptisine, palmatine, berberine and dehydrocorydaline. Reversed-phase systems with an octadecylsilane chemically bonded silica gel column using a mixture of sodium dodecyl sulfate, 0.05M tartaric acid and acetonitrile (0.5 : 62 : 38) and a mixture of sodium dodecyl sulfate, Britton-Robinson buffer (pH 3.0) and acetonitrile (0.5 : 56 : 34) as the mobile phases were suitable for the separation of tertiary alkaloids and quaternary alkaloids, respectively, in Corydalis Tuber.
- 社団法人日本薬学会の論文
- 1985-12-25
著者
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糸川 秀治
Tokyo College Of Pharmacy
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相楽 和彦
大正製薬(株)OTC開発研究所分析研究室
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伊藤 裕二
大正製薬(株)分析研
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糸川 秀治
東京薬科大学 薬学部
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尾島 光春
大正製薬(株)総合研究所
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相楽 和彦
Research Center, Taisho Pharmaceutical Co., Ltd.
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伊藤 裕二
Research Center, Taisho Pharmaceutical Co., Ltd.
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尾島 光春
Research Center, Taisho Pharmaceutical Co., Ltd.
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大島 俊幸
Research Center, Taisho Pharmaceutical Co., Ltd.
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須藤 桂一
Research Center, Taisho Pharmaceutical Co., Ltd.
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岬 哲夫
Research Center, Taisho Pharmaceutical Co., Ltd.
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相楽 和彦
大正製薬(株)分析研
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大島 俊幸
Research Center Taisho Parmaceutical Co. Ltd.
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岬 哲夫
Research Center Taisho Pharmaceutical Co. Ltd.
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須藤 桂一
大正製薬株式会社総合研究所
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大島 俊幸
大正製薬株式会社
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伊藤 裕二
大正製薬株式会社
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