Studies on Chemical Alterations of Nucleic Acids and Their Components. X. syntheses and Reactivties of 3-Aminopyrimidine Nucleosides
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概要
- 論文の詳細を見る
Treatment of pyrimidine nucleosides with hydroxylamine-O-esters (or hydroxylamine-O-aryl ethers) produced the corresponding 3-amino derivatives. 3-Aminouridine derivatives underwent deamination and acetylation to give uridines and 3-acetamidouridines, respectively. 3-Aminocytidine derivatives underwent, in addition to deamination, replacement with a sulfhydryl and cyclization with an orthoformate to give 3-amino-4-thiouridine and 1,2,4-triazolo [2,3-c] pyrimid-5 (6H)-one derivatives, respectively. Proton magnetic resonance and ultraviolet data of 3-amino derivatives are tabulated.
- 公益社団法人日本薬学会の論文
- 1975-04-25
著者
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川添 豊
Faculty of Pharmaceutical Sciences, Nagoya City University
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川添 豊
National Cancer Center Research Institute
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川添 豊
Faculty Of Pharmaceutical Sciences Nagoya City University
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前田 満和
National Cancer Center Research Institute
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