Studies on Chemical Carcinogens. IX. Homolytic Degradation of O, O'-Diacetyl-4-hydroxyaminoquinoline 1-Oxide : 1-Acetoxy-4-acetyloxyimino-1,4-dihydroquinoline
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概要
- 論文の詳細を見る
O, O'-Diacetyl-4-hydroxyaminoquinoline 1-oxide was found easily to liberate a considerable amount of acetic acid in inert organic solvents such as dioxane as well as in crystalline form. The acetic acid formation was regarded as being initiated by homolytic fission of N-O bond of the substituent hydroxyamino group and studied with a help of electron spin resonance spectroscopy. A brief discussion was made of the correlation of free radical formation with carcinogenesis of carcinogenic hydroxylamine derivatives.
- 公益社団法人日本薬学会の論文
- 1969-07-25
著者
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川添 豊
National Cancer Center Research Institute
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永田 親義
National Cancer Center Research Institute
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荒木 美佐子
National Cancer Center Research Institute
関連論文
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