Oxidation Reaction of Carcinogenic 4-Hydroxyaminoquinoline 1-Oxide
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概要
- 論文の詳細を見る
An amphoteric compound 4-hydroxyaminoquinoline 1-oxide(4-HAQO) was oxidized by oxygen to lose one electron from NHOH group of the molecule and to produce a stable free radical. This oxidative radical production was accelerated by addition of several kinds of oxidants. The UV-absorption of the free radical thus produced, showed its maximum at 455mμ. On the other hand, the oxidation of 4-HAQO was protected by the presence of such a reducing agent as ascorbic acid. As a result, the presence of such a reducing agent made it possible to record the UV spectrum of 4-HAQO in alkaline media.
- 社団法人日本薬学会の論文
- 1967-02-25
著者
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川添 豊
National Cancer Center Research Institute
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千原 呉郎
National Cancer Center Research Institute
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片岡 順子
National Cancer Center Research Institute
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柴田 幸子
Faculty of Pharmaceutical Science, Kitazato University
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今村 詮
National Cancer Center Research Institute
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永田 親義
National Cancer Center Research Institute
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柴田 幸子
Faculty Of Pharmaceutical Science Kitazato University
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永田 親義
国立がんセンター研究所生物物理部
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