Stereochemistry in Solution. III. Stereoselectivity in N-Quaternization and N-Oxygenation of α-Substituted Piperidines.
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Stereoselectivities in salt formation, N-methylation, N-ethylation, and N-oxygenation of α-substituted piperidines were examined in connection with the free energy-difference between the reaction intermediates in the axial and equatorial approaches of the reagent.
- 公益社団法人日本薬学会の論文
- 1967-09-25
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