Biological Photochemistry. I. The Correlation between the Photodynamical Behaviors and the Chemical Structures of Nucleic Acid-bases, Nucleosides, and Related Compounds in the Presence of Methylene-blue
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概要
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As a study on mechanism of photodynamic action with methylene-blue, the authors examined structural correlation of 40 kinds of nucleic acid-bases, nucleosides and related compounds with their photodynamic degradation by visible light-irradiation in the presence of methylene-bule. As a result, it became established that : 1) Above-mentioned compounds, in order to be easily photodynamically degradated, need to have the lactim structure with respect to N 1 and 3-position in pyrimidine moiety of purine ring. 2) Imidazol ring seems to be essential for photodegradation. 3) Existence of substituent in 8,9-position in purine didn't affect on photochemical reaction.
- 社団法人日本薬学会の論文
- 1965-09-25
著者
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実吉 峯郎
Faculty Of Pharmaceutical Sciences Hokkaido University
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千原 呉郎
National Cancer Center Research Institute
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全田 和子
Natinal Cancer Center Research Institute
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実吉 峯郎
Natinal Cancer Center Research Institute
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千原 呉郎
Natinal Cancer Center Research Institute
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