Resistance of Cyclocytidine to Cytidine Deaminase
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概要
- 論文の詳細を見る
Deamination of cytidine derivatives especially of cyclocytidine by mouse kidney cytidine deaminase was examined. Cyclocytidine was not deaminated at either pH6.5 or pH7.3 by the enzyme. Furthermore, cyclocytidine did not inhibit the deamination of aracytidine and ([I]/[S])_<0.5> value for cyclocytidine was over 100. As a result, cyclocytidine is found to be markedly active compound with resistance against cytidine deaminase.
- 社団法人日本薬学会の論文
- 1973-07-25
著者
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飯郷 正明
National Cancer Center Research Institute
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星昭 夫
国立がんセンター研究所薬効試験部
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榑谷 和男
Pharmacology Division, National Cancer Center Research Institute
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星 昭夫
Pharmacology Division, National Cancer Center Research Institute
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実吉 峯郎
Faculty Of Pharmaceutical Sciences Hokkaido University
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榑谷 和男
Pharmacology Division National Cancer Center Research Institute
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槫谷 和男
Pharmacology Division National Cancer Center Research Institute
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飯郷 正明
Pharmacology Division, National Cancer Center Research Institute
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実吉 峯郎
Pharmacology Division, National Cancer Center Research Institute
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Iigo M
National Cancer Center Research Institute
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