Studies on the Chemical Constituents of Rutaceous Plants. LX. Development of a Versatile Method for Syntheses of the Antitumor Benzo [c] phenanthridine Alkaloids. (9). Efficient Syntheses and Antitumor Activities of Nitidine and Related Nonphenolic Benzo
スポンサーリンク
概要
- 論文の詳細を見る
Several nonphenolic benzo [c] phenanthridine alkaloids including naturally occurring nitidine (1a) and avicine (1e) were synthesized in excellent yields through an efficient synthetic method developed by us. Antitumor activities of twelve alkaloids including four naturally occurring O_5-alkaloids [chelilutine (1g), chelirubine (1h), sanguilutine (1k), and sanguirubine (11)] against Sarcoma 180 were tested. The structure-activity relationship of these alkaloids is discussed.
- 社団法人日本薬学会の論文
- 1985-10-25
著者
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川鍋 恵理
Faculty Of Pharmaceutical Seicnces Chiba University
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石井 永
Faculty of Pharmaceutical Sciences, Chiba University
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石川 勉
Faculty of Pharmaceutical Sciences, Chiba University
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石川 勉
千葉大薬
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石川 勉
千葉大院薬
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星 昭夫
国立がんセンター研・薬効試験部
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石井 永
Faculty Of Pharmaceutical Sciences Chiba University
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猪俣 素子
Pharmacology Division National Cancer Center Research Institute
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星昭 夫
国立がんセンター研究所薬効試験部
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榑谷 和男
Pharmacology Division, National Cancer Center Research Institute
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星 昭夫
Pharmacology Division, National Cancer Center Research Institute
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石川 宗一
千葉大学薬学部
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榑谷 和男
Pharmacology Division National Cancer Center Research Institute
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槫谷 和男
Pharmacology Division National Cancer Center Research Institute
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市川 裕一郎
Faculty of Pharmaceutical Sciences, Chiba University
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石川 宗一
Faculty of Pharmaceutical Sciences, Chiba University
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Ishii H
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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市川 裕一郎
Faculty Of Pharmaceutical Sciences Chiba University
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