Fischer Indolization and Its Related Compounds. V. Indolization of Ethyl Pyruvate 2-Methoxyphenylhydrazone and Its N-Methyl Derivative with Protic Acids. Unpredictable Products and the Mechanism
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概要
- 論文の詳細を見る
Fischer indolization of ethyl pyruvate 2-methoxyphenylhydrazine (1) and its N-methyl derivative with protic acids give a variety of unpresumable indole products. Main products have been found to be 6-substituted indole derivatives formed by substitution of the methoxy group of the starting phenylhydrazone (1) with nucleophiles in the reaction medium. The tentative mechanism including an important key intermediate cation (15) is presented for the formation of the unexpected indole products.
- 公益社団法人日本薬学会の論文
- 1973-07-25
著者
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石井 永
Faculty of Pharmaceutical Sciences, Chiba University
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村上 泰興
Faculty of Pharmaceutical Sciences, University of Tokyo
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石井 永
Faculty Of Pharmaceutical Sciences Chiba University
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鈴木 義邦
Faculty Of Pharmaceutical Sciences Chiba University
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細谷 勝弘
Faculty of Pharmaceutical Sciences, Chiba University
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武田 春樹
Faculty of Pharmaceutical Sciences, Chiba University
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池田 仁三郎
Faculty of Pharmaceutical Sciences, Chiba University
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村上 泰興
東邦大・薬
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細谷 勝弘
Faculty Of Pharmaceutical Sciences Chiba University
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武田 春樹
Faculty Of Pharmaceutical Sciences Chiba University
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