Cesium Fluoride-Mediated Claisen Rearrangement of Aryl Propargyl Ether. Exclusive Formation of 2-Methylarylfuran and Its Availability as a Masked Salicylaldehyde
スポンサーリンク
概要
- 論文の詳細を見る
Claisen rearrangement of an aryl propargyl ether in the presence of CsF led to exclusive formation of 2-methylarylfuran in excellent yield. The result of a precise examination of the rearrangement is described. Satisfactory transformation of the 2-methylarylfuran to a salicylaldehyde derivative was achieved by stepwise oxidation. This combination of reactions serves as a useful method for regioselective introduction of a C_1 unit at the ortho position of a phenol group.
- 社団法人日本薬学会の論文
- 1992-05-25
著者
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鈴木 雅博
Hanno Research Center Chemistry Lab. Taiho Pharmaceutical Co. Ltd.
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石井 永
Faculty of Pharmaceutical Sciences, Chiba University
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石川 勉
Faculty of Pharmaceutical Sciences, Chiba University
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武田 直
Faculty of Pharmaceutical Sciences, Chiba University
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鈴木 雅博
Faculty of Pharmaceutical Sciences, Chiba University
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植木 聡
Faculty of Pharmaceutical Sciences, Chiba University
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石川 勉
千葉大薬
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石川 勉
千葉大院薬
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石井 永
Faculty Of Pharmaceutical Sciences Chiba University
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武田 直
Faculty Of Pharmaceutical Sciences Chiba University
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植木 聡
Faculty Of Pharmaceutical Sciences Chiba University
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