Synthesis of Toddacoumaquinone, a Coumarin-Naphthoquinone Dimer, and Its Antiviral Activities
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概要
- 論文の詳細を見る
Toddacoumaquinone (1), a coumarin-naphthoquinone dimer, was synthesized through Diels-Alder reaction between 8-(1-acetoxy-3-methyl-1,3-butadienyl)-5,7-dimethoxycoumarin (15) and 2-methoxy-1,4-benzoquinone (5). The activities of 1 against several viruses were examined. A weak activity (EC_<50>=10 μg/ml) was observed against HSV-1 and HSV-2,but no activity was seen against HIV-1.
- 社団法人日本薬学会の論文
- 1995-06-15
著者
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石井 永
Faculty of Pharmaceutical Sciences, Chiba University
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石川 勉
Faculty of Pharmaceutical Sciences, Chiba University
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石川 勉
千葉大薬
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石川 勉
千葉大院薬
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小竹 健一郎
千葉大薬
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小竹 健一郎
Faculty of Pharmaceutical Sciences, Chiba University
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石井 永
Faculty Of Pharmaceutical Sciences Chiba University
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