Fischer Indolization and Its Related Compounds. VI. Effect of Reagents and Substituent of the ortho-Substituted Phenylhydrazone on Abnormal Fischer Indolization
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概要
- 論文の詳細を見る
Treatment of ethyl pyruvate 2-methoxyphenylhydrazone (1) with Lewis acid gave 5-substituted and/or 5-methoxy-indole products with ethyl 7-methoxyindole-2-carboxylate (2) as a main product. It contrasts strikingly with the results reported in the previous paper^<1)> on a reaction center of the abnormal Fischer indolization. It was also found that differences of the acid strength of the reagent and of the electron density on a benzene ring due to introduction of some other additional substituents could be the determinant for the direction of the adnormal transformation.
- 社団法人日本薬学会の論文
- 1973-07-25
著者
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石井 永
Faculty of Pharmaceutical Sciences, Chiba University
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村上 泰興
Faculty of Pharmaceutical Sciences, University of Tokyo
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古瀬 徳夫
Faculty Of Pharmaceutical Sciences Chiba University
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石井 永
Faculty Of Pharmaceutical Sciences Chiba University
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細谷 勝弘
Faculty of Pharmaceutical Sciences, Chiba University
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池田 仁三郎
Faculty of Pharmaceutical Sciences, Chiba University
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村上 泰興
東邦大・薬
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細谷 勝弘
Faculty Of Pharmaceutical Sciences Chiba University
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