Studies on Chemical Carcinogens and Mutagens. XXVI. Chemical Properties and Mutagenicity of Alkyl Alkanesulfonates on Salmonella typhimurium TA100
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概要
- 論文の詳細を見る
The mutagenic and cytotoxic effects of 18 kinds of methyl, ethyl, and isopropyl esters of straight-chain alkanesulfonic acids including isethionic acid were investigated on Salmonella typhimurium TA100. In order to correlate these biological activities with the chemical and/or physicochemical properties, the hydrolytic rates (as a measure of alkylating ability) and the capacity factors (as a measure of hydrophobicity) were determined. Some structural correlations were apparent, although quantitative structure-activity relationships were not obtained.
- 公益社団法人日本薬学会の論文
- 1984-09-25
著者
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川添 豊
Faculty of Pharmaceutical Sciences, Nagoya City University
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幸田 光復
Faculty of Pharmaceutical Sciences, Nagoya City University
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川添 豊
名古屋市立大学薬学部
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幸田 光復
Faculty Of Pharmaceutical Sciences Nagoya City University
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羽倉 昌志
Faculty of Pharmaceutical Sciences, Nagoya City University
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川添 豊
Faculty Of Pharmaceutical Sciences Nagoya City University
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羽倉 昌志
Faculty Of Pharmaceutical Sciences Nagoya City University
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二宮 真一
Tokai Research Laboratories Daiichi Pure Chemicals Co. Ltd.
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二宮 真一
Faculty of Pharmaceutical Sciences, Nagoya City University
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