Absorption and Excretion of Drugs. XXVII. Effect of Nonionic Surface-Active Agents on Rectal Absorption of Sulfonamides
スポンサーリンク
概要
- 論文の詳細を見る
The rectal absorption of sulfonamides were reduced by the addition of various nonionic surface-active agents. This reduction depends upon the entrapment of drug in micelles. The drug in micelles was also absorbed a little, and therefore the enhancement of drug absorption were obtained by solubilization of the drug remained as a solid in solution. The mechanism of drug absorption in the presence of nonionic surface-active agent can be explained by the concept that there are two ways of the passage of the free drug and of the drug in micelles.
- 公益社団法人日本薬学会の論文
- 1965-08-25
著者
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村西 昌三
Faculty of Pharmaceutical Sciences, Kyoto University
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有田 隆一
Department Of Pharmacy Hokkaido University Hospital School Of Medicine Hokkaido University
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掛見 喜一郎
Faculty of Pharmaceutical Sciences, Kyoto University
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有田 隆一
Faculty Of Pharmaceutical Sciences Mukogawa Womenus University
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