Cardiac Effects of Salvia Miltiorrhiza/Dalbergia Odorifera Mixture, an Intravenously Applicable Chinese Medicine Widely Used for Patients With Ischemic Heart Disease in China
スポンサーリンク
概要
- 論文の詳細を見る
Chronotropic, inotropic and coronary vasodilator actions of the clinically available ampoule preparation of Salvia miltiorrhiza/Dalbergia odorifera mixture were examined using canine isolated, blood-perfused heart preparations. The mixture slightly decreased the sinoatrial rate and significantly increased coronary blood flow, but hardly affected the developed tension of the papillary muscle. The effect on coronary blood flow was induced by at least a 10-fold smaller dose than that which induced the chronotropic effect. These results were quite similar to those of a typical calcium channel blocker, verapamil, used in a previous study, suggesting that the Salvia miltiorrhiza/Dalbergia odorifera mixture may have potential as an anti-anginal drug.
- 社団法人日本循環器学会の論文
- 2002-01-20
著者
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Satoh Y
Department Of Pharmacology Interdisciplinary Graduate School Of Medicine And Engineering University
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Satoh Yoshioki
Department Of Pharmacology Interdisciplinary Graduate School Of Medicine And Engineering University
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Zhu Bing-mei
Department Of Pharmacology Interdisciplinary Graduate School Of Medicine And Engineering University
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Zhu Bing-mei
Department Of Pharmacology Yamanashi Medical University
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Takahara Akira
Department Of Internal Medicine National Kawatana Hospital
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Sugiyama Atsushi
Department Of Pharmacology Yamanashi Medical University
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Hashimoto Keitaro
Department Of Pharmacology Interdisciplinary Graduate School Of Medicine And Engineering University
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Hashimoto Keitaro
Department Of Pharmacology Interdisciplinary Graduate School Of Medicine And Engineering University
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Sugiyama Atsushi
Department Of Pharmacology. University Of Yamanashi Yamanashi Research Center Of Cliniacl Pharmacolo
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Sugiyama Atsushi
Department Of Chemistry College Of Science Rikkyo University
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Aikawa Tokiko
Department Of Pharmacology Toho University Faculty Of Pharmaceutical Sciences
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Sugiyama Atsushi
Department Of Pharmacology School Of Medicine Toho University
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Zhu Bing-Mei
Department of Pharmacology and Department of Human Science, Yamanashi Medical University
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HASHIMOTO Keitaro
Department of Pharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi
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HASHIMOTO Keitaro
Department of Phamacology, Yamanashi Medical University
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Sugiyama Atsushi
Department of Biotechnology, Faculty of Engineering, Kansai University
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Takahara Akira
Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Toho University
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