Identification and Determination of α-Dicarbonyl Compounds Formed in the Degradation of Sugars

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概要

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• The α-dicarbonyl compounds formed in the degradation of glucose and fructose were analyzed by HPLC using 2,3-diaminonaphthalene as derivatizing reagent, and identified as glucosone (GLUCO), 3-deoxyglucosone (3DG), 3-deoxyxylosone (3DX), tetrosone (TSO), triosone (TRIO), 3-deoxytetrosone (3DT), glyoxal (GO), and methylglyoxal (MGO). The results suggest that α-dicarbonyl compounds were formed from glucose via non-oxidative 3-deoxyglucosone formation and oxidative glucosone formation in glucose degradation. In addition, TRIO, GO, and MGO were also formed from glyceraldehyde as intermediate. The α-dicarbonyl compounds might be formed from glucose via these pathways in diabetes.

• 社団法人 日本農芸化学会の論文
• 2007-10-23

著者

• 早瀬 文孝

  明治大学農学部農芸化学科

• 早瀬 文孝

  日清ファルマ健康科学研究所

• Hayase Fumitaka

  Department of Agricultural Chemistry, Meiji University

• Yanagisawa Satoshi

  Department of Cardiology, Okazaki City Hospital

• WATANABE Hirohito

  Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The Un

• Watanabe Hirohito

  Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Science The Univ

• Hayase Fumitaka

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• Hayase Fumitaka

  Department Of Agricultural Chemistry The University Of Tokyo:(present Address) Department Of Agricul

• Hayase Fumitaka

  Department Of Agricultural Chemistry The University Of Tokyo : (present Address) Department Of Agric

• Hayase Fumitaka

  Central Research Laboratories Asahi Breweries Ltd.

• Hayase F

  Department Of Agricultural Chemistry Meiji University

• Arai Yumi

  Department Of Pediatrics Tokyo Women's Medical College

• USUI Teruyuki

  Department of Agricultural Chemistry, Faculty of Agriculture, Meiji University

• Hayase Fumitaka

  Dep. Of Agricultural Chemistry Fac. Of Agriculture Meiji Univ.

• Aida Kaoru

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• OHGUCHI Mio

  Department of Agricultural Chemistry, Faculty of Agriculture, Meiji University

• YOSHINO Miku

  Department of Agricultural Chemistry, Faculty of Agriculture, Meiji University

• KAWABATA Risa

  Department of Agricultural Chemistry, Faculty of Agriculture, Meiji University

• KISHIMOTO Junko

  Department of Agricultural Chemistry, Faculty of Agriculture, Meiji University

• Arai Yumi

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• Yanagisawa Satoshi

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• Yoshino Miku

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• Usui Teruyuki

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• Kishimoto Junko

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• Kawabata Risa

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

• Ohguchi Mio

  Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University

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