Isolation and Identification of 5-Methyl-imidazolin-4-one Derivative as Glyceraldehyde-Derived Advanced Glycation End Product
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概要
- 論文の詳細を見る
We isolated and identified the glyceraldehyde-derived advanced glycation product (AGE) formed from glyceraldehyde and Nα-acetylarginine. A major product was identified as Nα-acetyl-Nδ-(5-methyl-imidazolin-4-one-2-yl)-ornithine. The compound has been reported as methylglyoxal-derived AGE, MG-H1. This study suggests that MG-H1 is formed through both glyceraldehyde-related and methylglyoxal-related pathways. There is a possibility that MG-H1 becomes an index of injury to glyceraldehyde and methylglyoxal-related enzymes.
- 社団法人 日本農芸化学会の論文
- 2006-06-23
著者
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早瀬 文孝
明治大学農学部農芸化学科
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早瀬 文孝
日清ファルマ健康科学研究所
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Hayase Fumitaka
Department of Agricultural Chemistry, Meiji University
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WATANABE Hirohito
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The Un
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Watanabe Hirohito
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Science The Univ
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Hayase Fumitaka
Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University
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Hayase Fumitaka
Department Of Agricultural Chemistry The University Of Tokyo:(present Address) Department Of Agricul
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Hayase Fumitaka
Department Of Agricultural Chemistry The University Of Tokyo : (present Address) Department Of Agric
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Hayase Fumitaka
Central Research Laboratories Asahi Breweries Ltd.
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Hayase F
Department Of Agricultural Chemistry Meiji University
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USUI Teruyuki
Department of Agricultural Chemistry, Faculty of Agriculture, Meiji University
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Hayase Fumitaka
Dep. Of Agricultural Chemistry Fac. Of Agriculture Meiji Univ.
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Usui Teruyuki
Department Of Agricultural Chemistry Faculty Of Agriculture Meiji University
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