Participation of Endogenous Noradrenaline in the Relaese of ATP by High Potassium in the Rat Caudal Artery
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概要
- 論文の詳細を見る
Potassium (40 mM) evoked the release of adenine nucleotides and adenosine in rat isolated caudal arteries. This release was abolished by bunazosin. Endogenous noradrenaline was also released. Furthermore, the high potassium-induced purine release was abolished by rubbing the lumen of the vessel. These findings suggest that the high potassium releases endogenous noradrenaline, which subsequently elicits the release of ATP and related purines by acting on α<SUB>1</SUB>-adrenoceptors on the endothelial cell.
- 社団法人 日本薬理学会の論文
- 1995-05-01
著者
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KUNITOMO Masaru
Department of Pharmacology, School of Pharmaceutical Sciences, Mukogawa Women's University
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SHINOZUKA Kazumasa
Department of Pharmacology, School of Pharmaceutical Sciences, Mukogawa Women's University
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HATTORI Keisuke
Department of Cardiovascular Surgery, Gifu Prefectural Tajimi Hospital
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Kunitomo Masaru
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Mukogawa Women's University
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Kunitomo Masaru
Department Of Pharmacology Shimane Medical University
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Shimoura Keiko
Department of Pharmacology, Shimane Medical University
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Shinozuka Kazumasa
Department Of Pharmacology Faculty Of Pharmaceutical Science Mukogawa Women's University
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Shimoura Keiko
Department Of Pharmacology Faculty Of Pharmaceutical Science Mukogawa Women's University
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Hattori Keisuke
Department Of Cardiovascular Surgery Gifu Prefectural Tajimi Hospital
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Hattori Keisuke
Department Of Pharmacology Faculty Of Pharmaceutical Science Mukogawa Women's University
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Shinozuka Kazumasa
Department of Applied Chemistry, Faculty of Engineering, Yokohama National University
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