Effects of Heparin on the Inhibitory Activities of Human Urinary Trypsin Inhibitor (Ulinastatin) on Trypsin, Chymotrypsin and Leukocyte Elastase.
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概要
- 論文の詳細を見る
Effects of heparin on the inhibitory activities of human urinary trypsin inhibitor (ulinastatin) on trypsin, chymotrypsin and leukocyte elastase were studied. Heparin per se neither influenced the enzymatic activities nor changed the mode of inhibition of ulinastatin on the enzymes. In the presence of heparin, inhibitory effects of ulinastatin on trypsin were enhanced, whereas its effects on chymotrypsin and elastase were attenuated. These results suggest that the two functional domains in ulinastatin are differently affected by heparin.
- 公益社団法人 日本薬理学会の論文
著者
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Takaori Shuji
Department Of Pharmacology Shimane Medical University
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Shikimi Tadahiro
Department Of Fundamental Nursing School Of Nursing Shimane University
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Hattori Keisuke
Department Of Cardiovascular Surgery Gifu Prefectural Tajimi Hospital
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