MODIFICATION BY CADMIUM IONS OF <SUP>45</SUP>CALCIUM UPTAKE BY ISOLATED RABBIT AORTAE
スポンサーリンク
概要
- 論文の詳細を見る
Treatment with 0.5 mM Cd<SUP>++</SUP> suppressed the K<SUP>+</SUP> (30 mM)-stimulated uptake and influx of <SUP>45</SUP>Ca and abolished the K<SUP>+</SUP>-induced contraction in helical strips of rabbit aortae. The rapid and slow efflux of <SUP>45</SUP>Ca previously accumulated was not appreciably affected by Cd<SUP>++</SUP>. It is concluded that interference with the transmembrane influx of Ca<SUP>++</SUP> is a major mechanism of Cd<SUP>++</SUP> action.
- 社団法人 日本薬理学会の論文
著者
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Toda Noboru
Department of Pharmacology, Sniga University of Medical Sciences
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HATTORI Keisuke
Department of Cardiovascular Surgery, Gifu Prefectural Tajimi Hospital
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Shimoura Keiko
Department of Pharmacology, Shimane Medical University
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Toda Noboru
Department Of Pharmacology Shiga University Of Medical Science
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Shimoura Keiko
Department Of Pharmacology Faculty Of Pharmaceutical Science Mukogawa Women's University
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Hattori Keisuke
Department Of Cardiovascular Surgery Gifu Prefectural Tajimi Hospital
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TODA Noboru
Department of f Pharmacology, Faculty of Medicine, Kyoto University
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