Existense of a Human Urinary Trypsin Inhibitor (Urinastatin)-Like Substance in the Rat Brain.
スポンサーリンク
概要
- 論文の詳細を見る
A human urinary trypsin inhibitor, urinastatin (UT)-like immunoreactive substance with trypsin inhibitory activity, was demonstrated in certain brain regions in rats, especially the cerebral cortex, hippocampus and hypothalamus. Although this UT-like substance in the rat brain displayed an <I>N</I>-terminal amino acid sequence similar to that of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), it did not show any GAPDH activity. These results indicate that the UT-like substance in the rat brain is a protein different from GAPDH and indicates a localized distribution within certain brain regions partly related to learning and memory.
- 公益社団法人 日本薬理学会の論文
著者
-
Takaori Shuji
Department Of Pharmacology Shimane Medical University
-
Shikimi Tadahiro
Department Of Fundamental Nursing School Of Nursing Shimane University
-
Hattori Keisuke
Department Of Cardiovascular Surgery Gifu Prefectural Tajimi Hospital
関連論文
- ELECTROPHYSIOLOGICAL STUDY ON DOPAMINERGIC SYSTEM IN THE CAUDATE NUCLEUS
- Successful repair of atrial fibrillation by surgical ablation in a patient with persistent left superior vena cava and mitral stenosis
- PE-518 Long-Term Beneficial Effects of Statins Status Post Coronary Artery Bypass Grafting(PE087,Cardiovascular Surgery/CABG (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
- Asymptomatic severe carotid stenosis undergoing staged carotid artery stent and coronary artery bypass grafting : decisive role of brain single photon emission computed tomography
- PJ-637 Intraoperative Heart Rate Variability of a Cardiac Surgeon Himself and its Relevance to Clinical Performance in Coronary Artery Surgery(Cardiovascular surgery / CABG(02)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japane
- Safe Launching of a Newly Appointed Cardiac Surgery Unit at a Low-Volume Hospital With the Use of Cumulative Sum Analysis
- Comparison of Dopamine Contents in Lung Vasculature of Several Species
- Source of ATP, ADP, AMP and Adenosine Released from Isolated Rat Caudal Artery Exposed to Noradrenaline
- PHYSIOLOGICAL IMPLICATION OF THE L-ARGININE-NITRIC OXIDE PATHWAY IN CIRCULATION
- Participation of Endogenous Noradrenaline in the Relaese of ATP by High Potassium in the Rat Caudal Artery
- STUDIES OF CONNECTIONS BETWEEN LOCUS COERULEUS AND CEREBRAL CORTEX
- RELATIONSHIP BETWEEN THE ACTIVITY OF SERUM DOPAMINE-β-HYDROXYLASE AND THE ENZYMES RELATED TO HEPATIC FUNCTION
- MODIFICATION BY CADMIUM IONS OF 45CALCIUM UPTAKE BY ISOLATED RABBIT AORTAE
- DISTRIBUTION, UPTAKE AND RELEASE OF DOPAMINE IN RABBIT ARTERIES
- POSSIBLE MECHANISMS OF THE TRIPHASIC EFFECTS OF NEUROTENSIN ON THE RAT BLOOD PRESSURE
- INHIBITORY EFFECTS OF D-ISOMERS OF AROMATIC AMINO ACIDS ON THE DECARBOXYLATION OF L-5-HYDROXYTRYPTOPHAN
- EFFECTS OF DIAZEPAM, NITRAZEPAM AND BROTIZOLAM ON DOPAMINE TURNOVER IN THE OLFACTORY TUBERCLE, NUCLEUS ACCUMBENS AND CAUDATE NUCLEUS OF RATS
- ANTAGONIZING EFFECTS OF β-ADRENERGIC BLOCKERS ON LOCUS COERULEUS-INDUCED INHIBITION OF TRIGEMINAL NUCLEUS NEURONS
- IMPAIRMENT BY 6-HYDROXYDOPAMINE OF LOCUS COERULEUS-INDUCED MONOSYNAPTIC POTENTIAL IN THE SPINAL TRIGEMINAL NUCLEUS
- Changes in the ratio of urinary α1-microglobulin to ulinastatin levels in patients with Alzheimer-type dementia and vascular dementia
- SELECTIVE EFFECT OF ETHANOL ON THE VESTIBULAR NUCLEUS NEURONS IN THE CAT
- Localisation of Dopamine D_1-Like and D_2-Like Receptors in the Pulmonary Vasculature
- EXISTENCE OF A BRADYKININ-LIKE SUBSTANCE, AND INFLUENCE OF CARBACHOL AND ATROPINE ON KININ-FORMING AND DESTROYING ACTIVITIES, AND KININ AND KININOGEN CONTENTS IN RAT STOMACH
- A BRADYKININ-LIKE SUBSTANCE IN RAT STOMACH
- STUDIES ON KININ-FORMING ENZYME IN RAT STOMACH
- DOPAMINERGIC INHIBITION FROM SUBSTANTIA NIGRA OF CAUDATE NEURONS ACTIVATED BY CORTICAL STIMULATION
- MECHANISM OF RELAXANT ACTIVITIES OF UROTENSIN I, A NEUROPEPTIDE FROM FISH, ON ISOLATED RAT ARTERIES
- EFFECTS OF HARMALINE ON MEMBRANE EXCITABILITY AND ATPase ACTIVITY OF THE CRAYFISH GIANT AXON
- LOCAL ANESTHETIC ACTIVITY OF β-ADRENERGIC BLOCKING DRUGS IN THE CRAYFISH GIANT AXON, WITH REFERENCE TO CALCIUM ION
- Na, K-, Mg- AND HCO3-ADENOSINE TRIPHOSPHATASES IN THE RABBIT BRAIN CHOROID PLEXUS
- PANCREATIC LYSOSOMAL THIOL PROTEINASES AND INHIBITORS IN ACUTE PANCREATITIS INDUCED IN RATS
- PRODUCTION OF ANTIBODY TO APROTININ AND LOCATION OF THIS COMPOUND IN BOVINE TISSUE
- Gender and diet do not affect the urinary indices reflecting neuropsychiatric diseases
- SANDWICH ENZYME IMMUNOASSAY OF APROTININ
- Shift in drug-related awareness in students after completing a series of lectures on drugs in nursing curriculum
- THE EFFECT OF COCAINE ON THE 3H-NOREPINEPHRINE UPTAKE BY COLD STORED AORTA FROM RABBIT
- PREVENTIVE EFFECT OF FUSARIC ACID, A DOPAMINE β-HYDROXYLASE INHIBITOR, ON THE GASTRIC ULCERATION INDUCED BY WATER-IMMERSION STRESS IN RATS
- LEVELS OF TYROSINE AND TRYPTOPHAN IN THE PLASMA AND BRAIN OF SPONTANEOUSLY HYPERTENSIVE RATS
- CENTRAL CHOLINERGIC ACTIVATION BY CHLORFEN VINPHOS, AN ORGANOPHOSPHATE, IN THE RAT
- VASODILATORY EFFECTS OF ATRIAL NATRIURETIC PEPTIDE
- ACUTE EFFECTS OF NICOTINE ON GLYCOLYSIS OF RAT MYOCARDIUM WITH SPECIAL REFERENCE TO CARDIOVASCULAR EFFECTS
- THE EFFECT OF COCAINE ON CATECHOL-O-METHYL TRANSFERASE AND ON THE RESPONSE TO NOR-EPINEPHRINE OF RABBIT AORTIC STRIPS
- Dopamine Uptake by Rabbit Atria and Peripheral Arteries and Effects of Haloperidol
- EFFECT OF ALDOSTERONE ON RENAL Na, K-ACTIVATED ADENOSINE-TRIPHOSPHATASE ACTIVITY IN NON-ADRENALECTOMIZED RATS
- Effects of diphenhydramine iontophoretically applied onto neurons in the medial and lateral vestibular nuclei.
- EFFECTS OF DIPHENIDOL ON THE CENTRAL VESTIBULAR AND VISUAL SYSTEMS OF CATS
- SKELETAL CHANGES INDUCED BY DOPA DECARBOXYLASE INHIBITOR IN RATS
- Effects of anti-vertigo drugs on medial vestibular nucleus neurons activated by horizontal rotation.
- Effects of ethanol applied by electrosmosis on neurons in the lateral and medial vestibular nuclei.
- Relaxant effects of sauvagine on vascular strips of SHR and WKY with special reference on endogenously synthesized prostaglandins
- Ethanol inhibits vestibular and caloric nystagmus without affecting optokinetic nystagmus in rabbits.
- Effects of urotensin I and sauvagine on vascular strips of SHR and WKY
- Nitroarginine inhibits endothelium-derived relaxation.
- Existense of a Human Urinary Trypsin Inhibitor (Urinastatin)-Like Substance in the Rat Brain.
- Relationships between Urinary Levels of Ulinastatin and .ALPHA.1-Microglobulin and the Severity of Alzheimer-Type or Vascular Dementia.
- Effects of Heparin on the Inhibitory Activities of Human Urinary Trypsin Inhibitor (Ulinastatin) on Trypsin, Chymotrypsin and Leukocyte Elastase.
- Inhibition by intravenously administered sodium bicarbonate of neuronal activity in medial vestibular nucleus neurons.
- Inhibitory effects of L-threo-DOPS, an L-noradrenaline precursor, on locus coeruleus-originating neurons in the caudate nucleus.
- Hypertensive Effects of Nitroarginine:Comparison between WKY and SHRSP
- Characteristics of ethacrynic acid highly sensitive Mg2+-ATPase in microsomal fractions of the rat brain : Functional molecular size, inhibition by SITS and stimulation by Cl-.
- Solubilization and separation of ethacrynic acid(EA) highly sensitive and EA less sensitive Mg2+-ATPases in the rat brain.
- A noradrenaline-induced inhibition from locus coeruleus of nucleus accumbens neuron receiving input from hippocampus.
- The enhancing effect of gelatin on aprotinin activity.
- Immunochemical and kinetic evidence that heparin enhances aprotinin activity.
- PHARMACOLOGICAL STUDIES ON TRANSMISSION IN THE CENTRAL VISUAL PATHWAY IN RELATION TO EFFECTS OF PENTOBARBITAL
- Muscarinic receptor-mediated inhibition of dopaminergic excitatory input to caudate neurons from the substantia nigra.
- THE EFFECT OF DRUGS ON THE CARDIAC MEMBRANE POTENTIALS IN THE RABBIT:II. AURICULAR MUSCLE FIBERS AND THE SINOATRIAL NODE
- THE EFFECT OF LSD AND RESERPINE ON THE CENTRAL NERVOUS SYSTEM OF THE CAT:THE ANTAGONISM BETWEEN LSD AND CHLORPROMAZINE OR RESERPINE