LENGTH-PASSIVE TENSION RELATIONSHIPS IN CEREBRAL AND PERIPHERAL ARTERIES ISOLATED FROM SPONTANEOUSLY HYPERTENSIVE AND NORMOTENSIVE RATS
スポンサーリンク
概要
- 論文の詳細を見る
The length-passive tension relationship was compared in helically-cut strips of the basilar, renal and mesenteric arteries and the aorta isolated from Kyoto Wistar (WKY) rats and stroke-resistant (SHRSR) and stroke-prone spontaneously hypertensive rats (SHRSP). Passive tension developed by the same magnitude of rapid stretch was greater in basilar arteries than in the other arteries and aortae. The length-tension curve shifted toward the tension axis in basilar arteries and aortae isolated from SHRSP as compared with those isolated from WKY, whereas the curves in mesenteric and renal arteries from SHRSP, SHRSR and WKY were not significantly different. It is concluded that the distensibility of various arteries isolated from rats differs, and the cerebral artery becomes less distensible during the persistence of hypertension and the rat become prone to stroke.
- 社団法人日本循環器学会の論文
- 1982-10-20
著者
-
MIYAZAKI Mizuo
Department of Pharmacology, Osaka Medical College
-
Miyazaki Mizuo
Department Of Pharmacology Shiga University Of Medical Sciences
-
Toda Noboru
Department of Pharmacology, Sniga University of Medical Sciences
-
Okunishi Hideki
Department of Pharmacology, Shimane Medical University
-
Okunishi H
Shimane Medical Univ. Shimane Jpn
-
Okunishi Hideki
Department Of Pharmacology Shiga University Of Medical Sciences
-
Toda Noboru
Department Of Pharmacology Shiga University Of Medical Sciences
-
Toda Noboru
Department Of Pharmacology Shiga University Of Medical Science
-
Miyazaki Mizuo
Department Of Pharmacoldgy Osaka Medical College
-
TODA Noboru
Department of f Pharmacology, Faculty of Medicine, Kyoto University
関連論文
- New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Chymase as an Important Target to Prevent Organ Damage
- Long-Term Angiotensin II Blockade May Improve Not Only Hyperglycemia but Also Age-Associated Cardiac Fibrosis
- Pitavastatin reduces oxidative stress and attenuates intermittent hypoxia-induced left ventricular remodeling in lean mice
- OE-235 Evidence of Plaque Neovascularization and Effects of Angiotensin Receptor Blocker in Cholesterol-Fed Monkey(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-307 Imidapril Attenuates MMP-9 Level More Effectively than Losartan in Patients with Acute Myocardial Infarction Treated by Primary-Percutaneous Coronary Intervention(Acute myocardial infarction, clinical(diagnosis/treatment)(02)(IHD),Oral Presentation
- PE-317 Angiotensin Receptor 1 Blocker Inhibits Atherosclerotic Changes of Aortic Valve by Preserving Endothelial Cells and Inhibiting Transformation into Osteoblast Phenotype(Vascular heart disease/Pericarditis/Cardiac tumor-2 (M) PE53,Poster Session (Eng
- Evidence for Abundant Presence of Chymase-Positive Mast Cells in the Kidneys of Patients with Immunoglobulin A Nephropathy : Effect of Combination Therapy with Prednisolone and Angiotensin II Receptor Blocker Valsartan
- Inhibition of Human Chymase by Suramin
- Angiotensin II Type 1 Receptor Antagonist, TCV-1 16, Prevents Neointima Formation in Injured Arteries in the Dog
- IS005 Vascular Smooth Muscle Cell(VSMC)-Specific Overexpression of Angiotensin type2(AT2)Receptor Causes Endothelium-dependent Vasodilation via bradykinin/NO/cGMP pathway
- Inhibition of the Angiotensin II Type 1 Receptor by TCV-116: Quantitation by In Vitro Autoradiography
- P218 INTERACTION OF VASCULAR SMOOTH MUSCLE CELLS(VSMC) WITH EXTRACELLULAR MATRIX(ECM) : EFFECTS OF THE PURIFIED HUMAN CHYMASE ON VSMC ATTACHMENT TO ECM
- Chymase inhibition attenuates tetrachloride-induced liver fibrosis in hamsters
- Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet
- Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats
- Anti-Atherosclerotic Effects of Dihomo-γ-Linolenic Acid in ApoE-Deficient Mice
- Chymase Inhibition Provides Pancreatic Islet Protection in Hamsters With Streptozotocin-Induced Diabetes
- Involvement of Vascular Angiotensin II-Forming Enzymes in the Progression of Aortic Abdominal Aneurysms in Angiotensin II-Infused ApoE-Deficient Mice
- Significance of chymase-dependent angiotensin II formation in the progression of human liver fibrosis
- Characterization of Recombinant Human Chymase Expressed in Escherichia coli
- -96-HYPOTENSIVE EFFECT OF A SPECIFIC INHIVITOR OF HUMAN RENIN
- OJ-062 Effect of Chymase Inhibition by NK-3201 on Hypoxia-Induced Left Ventricular Remodeling in Mice(Cardiovascular pharmacology, basic/clinical(02)(H),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- The Significance of Chymase in the Progression of Abdominal Aortic Aneurysms in Dogs
- OJ-199 Role of Chymase and MMPs in Angiotensin II-induced Abdominal Aortic Aneurysms(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- The Effects of Chymase on Matrix Metalloproteinase-2 Activation in Neointimal Hyperplasia after Balloon Injury in Dogs
- Tissue Angiotensin II Generating System by Angiotensin-Converting Enzyme and Chymase
- PJ-418 Effects of Chymase Inhibition on the Stenosis after Polytetrafluoroethylene Grafts Implantation(Restenosis, basic/clinical-5 (IHD) PJ71,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PE-278 Chymase Inhibition Prevents the Progression of Abdominal Aortic Aneurysm in Dogs(Peripheral circulation-5 (H) PE47,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Chymase Inhibition Prevents Cardiac Fibrosis and Dysfunction after Myocardial Infarction in Rats
- Role of Chymase-Dependent Angiotensin II Formation in Regulating Blood Pressure in Spontaneously Hypertensive Rats
- The Effect of Chymase Inhibition on Arteriovenous Fistula Stenosis in Dogs (Peripheral Circulation/Vascular Disease 6 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- A Potent Chymase Inhibitor, Suc-Val-Pro-Phe(p)(OPh)(2), Suppresses the Development of Abdominal Aortic Aneurysm in Dogs(Valvular Heart Disease/Pericarditis/Cardiac Tumor 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Effect of Chymase-Dependent Transforming Growth Factor β on Peritoneal Adhesion Formation in a Rat Model
- A Single Treatment With a Specific Chymase Inhibitor, TY-51184, Prevents Vascular Proliferation in Canine Grafted Veins
- PJ-043 An Antiarrhythmic Effect of A Chymase Inhibitor After Myocardial Infarction(Acute Myocardial Infarction, Basic 2 (IHD) : PJ8)(Poster Session (Japanese))
- Impact of Chymase Inhibitor on Cardiac Function and Survival after Myocardial Infarction
- Oral Administration of a Specific Chymase Inhibitor, NK3201, Suppresses the Development of Aneurysmal Dilatation on Hamster Experimental Aneurysm Model
- Possible Roles of Angiotensin II-Forming Enzymes, Angiotensin Converting Enzyme and Chymase-like Enzyme, in the Human Aneurysmal Aorta
- Effect of Chymase Inhibitor on Vascular Proliferation
- Development of the Chymase Inhibitor as an Anti-Tissue-Remodeling Drug : Myocardial Infarction and Some Other Possibilities
- Therapeutic Potential of a Specific Chymase Inhibitor in Atopic Dermatitis
- Recombinant Human Chymase Produced by Silkworm-Baculovirus Expression System : Its Application for a Chymase Detection Kit
- Oral Administration of a Novel Chymase Inhibitor, NK3201, Prevents Peritoneal Adhesion Formation in Hamsters
- Inhibition of chymase improves cardiac function via suppression of fibrosis in hamster cardiomyopathic model
- Role of chymase in the development of aneurysmal formation; An experimental aneurysm model
- Beneficial Effects of Angiotensin-Converting Enzyme Inhibition in Adriamycin-Induced Cardiomyopathy in Hamsters
- Possible Roles of Cardiac Chymase After Myocardial Infarction in Hamster Hearts
- Local Angiotensin II-Generating System in Vascular Tissues: the Roles of Chymase
- An Orally Active Chymase Inhibitor, BCEAB, Suppresses Heart Chymase Activity in the Hamster
- The Functional Ratio of Chymase and Angiotensin Converting Enzyme in Angiotensin I-Induced Vascular Contraction in Monkeys, Dogs and Rats
- OE-273 Involvement of Superoxide in Angiotensin II-induced Hypertension is Unmasked by Development of Nox1-deficient Mice(Hypertension, basic-1 (H) OE46,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
- Trans-Differentiation of Bone Marrow Monocyte-Lineage Cells to Endothelial-Like Cells and Reendothelialization on Injured Endothelium by MCP-1-Dependent Adhesion
- Characteristics of Monkey Tryptase Purified From Cheek Pouch Vascular Tissues
- PJ-312 Intermittent Hypoxia Accelerates Cardiovascular Remodeling due to Postprandial Hyperglycemia in Lean Mice(PJ053,Metabolic Syndrome 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-425 Left Ventricular Remodeling Induced by Intermittent Hypoxia : Role of gp91phox Subunit of NADPH Oxidase(Heart failure, basic(04)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-398 Nuclear Factor-κ B Activation Accelerates Cardiac Hypertrophy, Interstitial Fibrosis, and Oxidative Stress in Diabetic Rats Exposed to Intermittent Hypoxia(Chronic coronary heart disease/Remodeling-2, The 71st Annual Scientific Meeting of the Japan
- Pulmonary Edema Induced by Angiotensin II in Rats
- Nitric Oxide-Mediated Neurogenic Relaxation in Monkey Mesenteric Veins
- EFFECT OF INTRA-AORTIC BALLOON PUMPING AND CALCIUM ANTAGONIST FOR REDUCING CORONARY REPERFUSION INJURY
- Characterization of nitrergic function in monkey penile erection in vivo and in vitro
- G-CSF Treatment Inhibits Neointimal Hyperplasia Associated with Endothelial Progenitor Cell Mobilization and Acceleration of Reendothelialization in Catorid Artery Injuty Model(Restenosis after Angioplasty, Basic/Clinical 5 (IHD), The 69th Annual Scientif
- Critical Role of Tyrosine Kinase PYK2 in eNOS Activation Revealed by Analysis of PYK2 Knockout Mice(Endothelium/NO 5 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-417 Tyrosine Kinase PYK2 activates eNOS and subsequently regulates Vascular Tonus and Angiogenesis, revealed by its Knock-out Mice(Endothelium/NO 5 (H) : OJ51)(Oral Presentation (Japanese))
- eNOS Activation and Its Vascular Functions Critically Requires the Presence of Tyrosine Kinase PYK2
- OJ-028 G-CSF Treatment Inhibits Neointimal Formation after Arterial Injury through the Mobilization of Endothelial Progenitor Cell and Acceleration of Reendothelialization(Restenosis, basic/clinical-1 (IHD) OJ5,Oral Presentation (Japanese),The 70th Annive
- Inhibition of Vascular Angiotensin-Converting Enzyme by Telmisartan via the Peroxisome Proliferator-Activated Receptor γ Agonistic Property in Rats
- Inhibition of Matrix Metalloproteinase-9 Activity by Trandolapril after Middle Cerebral Artery Occlusion in Rats
- PROTECTION OF CORONARY REPERFUSION INJURY BY A CALCIUM ANTAGONIST
- LENGTH-PASSIVE TENSION RELATIONSHIPS IN CEREBRAL AND PERIPHERAL ARTERIES ISOLATED FROM SPONTANEOUSLY HYPERTENSIVE AND NORMOTENSIVE RATS
- Inhibition of Dog Renin Activity by Pepstatin A : VIII CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- Trandolapril Reduces Infarction Area after Middle Cerebral Artery Occlusion in Rats
- Effects of a Lipoxygenase Inhibitor, Panaxynol, on Vascular Contraction Induced by Angiotensin II
- Significance of Angiotensin II Receptor Blocker Lipophilicities and Their Protective Effect against Vascular Remodeling
- THE REGIONAL DIFFERENCES OF THE CONTRACTILE RESPONSE TO VASOACTIVE SUBSTANCES IN ISOLATED DOG CORONARY ARTERIES : Coronary Circulation : 46th Annual Scientific Meeting, Japanese Circulation Society
- Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats
- EFFECTS OF ELCATONIN ON PLASMA AND URINE ELECTROLYTES IN INFANT BEAGLES
- Functional Studies on Blockade by Neosurugatoxin of Nicotinic Receptors in Nitroxidergic and Sensory Nerve Terminals and Intramural Ganglionic Cells
- Comparative Effects of Candesartan and Amlodipine in a Monkey Atherosclerotic Model
- Significant Target Organs for Hypertension and Cardiac Hypertrophy by Angiotensin-Converting Enzyme Inhibitors
- Significance of Vascular Angiotensin-Converting Enzyme in the Depressor Mechanism by Angiotensin-Converting Enzyme Inhibitors
- Inhibition by Adrenomedullin of the Adrenergic Neurogenic Response in Canine Mesenteric Arteries
- Pharmacological Profiles of a Novel Non-peptide Angiotensin II Type I Receptor Antagonist HR720 In Vitro and In Vivo
- EFFECTS OF GLUCAGON ON THE RENAL HEMODYNAMICS IN THE DOG
- RENIN INHIBITORY EFFECT OF N-ACETYL-PEPSTATIN
- REGIONAL AND SPECIES DIFFERENCES IN THE RESPONSE OF ISOLATED ARTERIES TO ANGIOTENSIN II
- Purification of L-Glutamate Decarboxylase from Monkey Brain
- EFFECTS OF RENAL VENOUS PRESSURE ELEVATION ON RENAL HEMODYNAMICS, URINE FORMATION AND RENIN RELEASE
- CONTROL OF RENIN SECRETION IN THE ANESTHETIZED DOG (3) EFFECTS OF HYPERTONIC MANNITOL INFUSION
- Control of Renin Secretion in the Anesthetized Dog 2) Relationship between Renin Secretion, Plasma Sodium Concentration and GFR in the Perfused Kidney
- Preface
- CONTRACTILE RESPONSES OF ISOLATED DOG MESENTERIC ARTERIES TO ANGIOTENSIN I, II AND III
- Purification of L-Glutamate Decarboxylase from Monkey Brain
- Irbesartan Prevents Metabolic Syndrome in Rats via Activation of Peroxisome Proliferator-Activated Receptor γ
- New Approaches to Blockade of the Renin-Angiotensin-Aldosterone System : Chymase as an Important Target to Prevent Organ Damage
- Effects of Acarbose on the Acceleration of Postprandial Hyperglycemia-Induced Pathological Changes Induced by Intermittent Hypoxia in Lean Mice
- Irbesartan Prevents Metabolic Syndrome in Rats via Activation of Peroxisome Proliferator-Activated Receptor γ
- Multiple Mechanisms for the Action of Chymase Inhibitors
- Outside Fibroblasts Play a Key Role in the Development of Inner Neointima After the Implantation of Polytetrafluoroethylene Grafts
- Alpha adrenoceptor subtypes responsible for dopamine-induced mesenteric vein contraction.
- KRI-1314: An Orally Effective Inhibitor of Human Renin.