β_1-Adrenoceptor-Mediated Relaxation by Norepinephrine in Dog Hepatic Arteries
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概要
- 論文の詳細を見る
Dog hepatic arterial strips treated with prazosin responded to norepinephrine with concentration-related, endothelium-independent relaxations, the maximal response being 81.7% of the papaverineinduced maximal relaxation that was markedly greater than that in renal arteries. The norepinephrineinduced relaxation in hepatic arteries was significantly attenuated by metoprolol but not influenced by butoxamine. Relaxant responses to norepinephrine of dog hepatic arteries appear to be mediated by the β<SUB>1</SUB>-adrenoceptor subtype, like those of coronary arteries. Evidence for functioning of the β<SUB>1</SUB>-subtype in hepatic arteries would contribute to the analysis of neural and hormonal regulation of blood flow in the liver.
- 社団法人 日本薬理学会の論文
- 1997-01-01
著者
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Toda Noboru
Department of Pharmacology, Sniga University of Medical Sciences
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OKAMURA Tomio
Department of Pharmacology, Shiga University of Medical Science
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Okamura Tomio
Department Of Pharmacology Shiga University Of Medical Sciences
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Okamura Tomio
Department Of Pharmacology
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Toda Noboru
Department Of Pharmacology Shiga University Of Medical Sciences
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Toda Noboru
Department Of Pharmacology Shiga University Of Medical Science
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SHIRAISHI Susumu
Department of Pharmacology, Shiga University of Medical Sciences
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Shiraishi Susumu
Department Of Pharmacology Shiga University Of Medical Sciences
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TODA Noboru
Department of f Pharmacology, Faculty of Medicine, Kyoto University
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